2. Signaling Pathways
  3. Immunology/Inflammation
  4. SphK
  5. SphK1 Isoform

SphK1

 

SphK1 Related Products (8):

Cat. No. Product Name Effect Purity
  • HY-119016A
    SK1-​I hydrochloride
    		Inhibitor 99.49%
    SK1-I hydrochloride (BML-258 hydrochloride), an analog of sphingosine, is an isozyme-specific competitive SPHK1 inhibitor with a Ki value of 10 µM.
  • HY-101572
    MHP
    		Activator 98.54%
    MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production.
  • HY-124042
    K6PC-5
    		Activator 99.85%
    K6PC-5, a ceramide derivative, is a sphingosine kinase 1(SPHK1) activator and elicites a rapid transient increase in intracellular calcium levels.
  • HY-150615
    SphK1-IN-2
    		Inhibitor
    SphK1-IN-2 is a potent, selective SphK1 inhibitor with IC50 values of 19.81 nM and ＞10 μM for SphK1 and SphK2, respectively.
  • HY-148707
    SphK1&2-IN-1
    		Inhibitor
    SphK1&2-IN-1 is a SphK inhibitor targeting to SphK1 and SphK2.
  • HY-148262
    SphK1-IN-3
    		Inhibitor
    SphK1-IN-3 is an effective sphingosine kinase-1 (SphK1) inhibitor.
  • HY-143296
    SphK1-IN-1
    		Inhibitor
    SphK1-IN-1 (compound 48) is a SphK1 inhibitor with effective antitumor activity.
  • HY-147282
    Amgen-23
    		Inhibitor
    Amgen-23 (compound 23) is a potent sphingosine kinases (SPHK) inhibitor with IC50 values of 20 nM and 1.6 μM for SPHK1 and SPHK2, respectively.