1. Immunology/Inflammation
  2. SphK
  3. SLM6031434 hydrochloride

SLM6031434 hydrochloride 

Cat. No.: HY-120268A
Handling Instructions

SLM6031434 hydrochloride is a highly selective sphingosine kinase 2 (SphK2) inhibitor with Kis of 0.4 μM, 0.5 μM, >20 μM, 22 μM for mSphK2, rSphK2, mSphK1 and rSphK1, respectively. SLM6031434 hydrochloride decrease Sphingosine 1-phosphate (S1P) levels in U937 monocytic leukemia cells. SLM6031434 hydrochloride has the potential for renal fibrosis research.

For research use only. We do not sell to patients.

SLM6031434 hydrochloride Chemical Structure

SLM6031434 hydrochloride Chemical Structure

CAS No. : 1897379-34-8

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Description

SLM6031434 hydrochloride is a highly selective sphingosine kinase 2 (SphK2) inhibitor with Kis of 0.4 μM, 0.5 μM, >20 μM, 22 μM for mSphK2, rSphK2, mSphK1 and rSphK1, respectively. SLM6031434 hydrochloride decrease Sphingosine 1-phosphate (S1P) levels in U937 monocytic leukemia cells. SLM6031434 hydrochloride has the potential for renal fibrosis research[1][2].

Molecular Weight

489.96

Formula

C22H31ClF3N5O2

CAS No.
SMILES

N=C(N1[[email protected]](C2=NC(C(C=C3)=CC(C(F)(F)F)=C3OCCCCCCCC)=NO2)CCC1)N.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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SLM6031434 hydrochloride
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