SphK1-IN-4
SphK1-IN-4 (Compound 6b) is a sphingosine kinase 1 (SphK1) inhibitor. SphK1-IN-4 can be used for the research of cancer, such as lung cancer.
For research use only. We do not sell to patients.
- CAS No.: 160149-21-3
- Formula: C16H9ClN2O2
- Molecular Weight:296.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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SphK1 |
SphK1-IN-4 exhibit potent and selective cytotoxicity toward A549 and MCF-7 cells with IC50 values of 0.85 and 1.9 μM. SphK1-IN-4 is non-toxic toward Vero cells (LD50 >100 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 160149-21-3
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Molecular Weight 296.71
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Formula C16H9ClN2O2
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SMILES
O=C1OC2=C(C=C(Cl)C=C2)C=C1C3=NC4=CC=CC=C4N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)