1. Immunology/Inflammation
  2. SphK
  3. Amgen-23

Amgen-23 

Cat. No.: HY-147282
Handling Instructions

Amgen-23 (compound 23) is a potent sphingosine kinases (SPHK) inhibitor with IC50 values of 20 nM and 1.6 μM for SPHK1 and SPHK2, respectively. Amgen-23 can be used for researching anticancer.

For research use only. We do not sell to patients.

Amgen-23 Chemical Structure

Amgen-23 Chemical Structure

CAS No. : 1448706-15-7

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Description

Amgen-23 (compound 23) is a potent sphingosine kinases (SPHK) inhibitor with IC50 values of 20 nM and 1.6 μM for SPHK1 and SPHK2, respectively. Amgen-23 can be used for researching anticancer[1].

IC50 & Target[1]

SphK1

20 nM (IC50)

SphK2

1.6 μM (IC50)

Molecular Weight

478.43

Formula

C23H25Cl2N3O2S

CAS No.
SMILES

ClC(C=C1C2=CSC(NC3=CC=C(C=C3)CCN4[[email protected]](C[[email protected]](CC4)O)CO)=N2)=C(C=C1)Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Amgen-23
Cat. No.:
HY-147282
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