1415662-57-5
1415662-57-5
Chemical Structure
SphK1&2-IN-1
- CAS No.: 1415662-57-5
- Formula:C14H14N2O3S
- Molecular Weight:290.34
IUPAC Name: (E)-3-(3,4-dimethoxyphenyl)-N-(thiazol-2-yl)acrylamide
InChIKey: SMRXKMFZQYOXSX-GQCTYLIASA-N
SMILES: COC1=C(C=CC(/C=C/C(NC2=NC=CS2)=O)=C1)OC
Biological Activity: SphK1&2-IN-1 is a SphK inhibitor targeting to SphK1 and SphK2. SphK1&2-IN-1 has thermal stability[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SphK1&2-IN-1 | 98.47% | SphK1&2-IN-1 is a SphK inhibitor targeting to SphK1 and SphK2. SphK1&2-IN-1 has thermal stability. | ||||||||||||||||||||
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References
- [1]. Vogt D, et al. Design, synthesis and evaluation of 2-aminothiazole derivatives as sphingosine kinase inhibitors. Bioorg Med Chem. 2014 Oct 1;22(19):5354-67. [Content Brief]
- [2]. Nong W, et al. Synthesis and biological evaluation of a new series of cinnamic acid amide derivatives as potent haemostatic agents containing a 2-aminothiazole substructure. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4506-4511. [Content Brief]
