Methyl 3,4-dimethoxycinnamate
Methyl 3,4-dimethoxycinnamate is an inhibitor of uredospore germination. Methyl 3,4-dimethoxycinnamate also inhibits global DNA methylation in in Hep3B cells.
For research use only. We do not sell to patients.
- CAS No.: 5396-64-5
- Formula: C12H14O4
- Molecular Weight:222.24
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | IC50 |
>30 μg/mL
Compound: 4k
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Inhibitory concentration required against A 431 human epidermoid carcinoma cell line
Inhibitory concentration required against A 431 human epidermoid carcinoma cell line
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[PMID: 11354370] |
| B16 | IC50 |
>30 μg/mL
Compound: 4k
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Inhibitory concentration against B16 murine melanoma cell line
Inhibitory concentration against B16 murine melanoma cell line
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[PMID: 11354370] |
| HCT-116 | IC50 |
>30 μg/mL
Compound: 4k
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Inhibitory concentration against HCT 116 human colon cancer cell line
Inhibitory concentration against HCT 116 human colon cancer cell line
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[PMID: 11354370] |
Chemical Information
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CAS No. 5396-64-5
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Appearance Solid
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Molecular Weight 222.24
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Formula C12H14O4
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Color White to off-white
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SMILES
O=C(OC)/C=C/C1=CC=C(OC)C(OC)=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Macko V, et al. Self-inhibitor of bean rust uredospores: methyl 3,4-dimethoxycinnamate. Science. 1970 Oct 30;170(3957):539-40. [Content Brief]
[2]. Castro-Vazquez D, et al. Methyl benzoate and cinnamate analogs as modulators of DNA methylation in hepatocellular carcinoma. Chem Biol Drug Des. 2022 Aug;100(2):245-255. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Methyl 3,4-dimethoxycinnamate Related Classifications
HY-W242821 Related Classifications
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