1491909-40-0
1491909-40-0
Chemical Structure
RB-042
- CAS No.: 1491909-40-0
- Formula:C25H43NO
- Molecular Weight:373.63
IUPAC Name: (R)-(1-(4-dodecylphenethyl)pyrrolidin-2-yl)methanol
InChIKey: PNEOFQRNMJSTMT-RUZDIDTESA-N
SMILES: C(CC1=CC=C(CCCCCCCCCCCC)C=C1)N2[C@@H](CO)CCC2
Biological Activity: RB-042 is a SK1 and SK2 inhibitor with IC50 values of 5.3 μM and 5.0 μM, respectively. RB-042 is applicable to the research of inflammatory diseases[1][2].
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RB-042 | RB-042 is a SK1 and SK2 inhibitor with IC50 values of 5.3 μM and 5.0 μM, respectively. RB-042 is applicable to the research of inflammatory diseases. | |||||||||||||||||||||
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References
- [1]. Baek DJ, et al. Structure-activity relationships and molecular modeling of sphingosine kinase inhibitors. J Med Chem. 2013;56(22):9310-9327. [Content Brief]
- [2]. Shrestha J, et al. Synthesis of Novel FTY720 Analogs with Anticancer Activity through PP2A Activation. Molecules. 2018;23(11):2750. Published 2018 Oct 24. [Content Brief]
Keywords
