1. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  2. Histamine Receptor
  3. Dexchlorpheniramine

Dexchlorpheniramine is an potent and blood-brain barrier (BBB) penetrant histamine 1 (H1) receptor antagonist with anticholinergic properties. Dexchlorpheniramine can be used for researching allergies.

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Dexchlorpheniramine

Dexchlorpheniramine Estructura química

No. CAS : 25523-97-1

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Descripciòn

Dexchlorpheniramine is an potent and blood-brain barrier (BBB) penetrant histamine 1 (H1) receptor antagonist with anticholinergic properties. Dexchlorpheniramine can be used for researching allergies[1].

IC50 & Target

H1 Receptor

 

In Vivo

Dexchlorpheniramine (2-10 mg/kg; IP, single dosage) and Ranitidine (10-50 mg/kg) co-administration can simultaneous blockade of H1 and H2 receptors, and protects both the cortical plate and the white matter against the excitotoxic challenge in Swiss pups pretreated with IL-9[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

274.79

Fòrmula

C16H19ClN2

No. CAS
SMILES

CN(CC[C@@H](C1=CC=C(Cl)C=C1)C2=NC=CC=C2)C

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Dexchlorpheniramine
Cat. No.:
HY-117501
Cantidad:
MCE Japan Authorized Agent: