DMT-2'-O-MOE-rA(Bz) phosphoramidite

Name: DMT-2'-O-MOE-rA(Bz) phosphoramidite
Brand: MedChemExpress
SKU: HY-104017
Rating: 4.5 (0 reviews)

Cat. No.: HY-104017 Purity: 98.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenine nucleoside analog. DMT-2'-O-MOE-rA(Bz) phosphoramidite can be used in research on oligonucleotide synthesis.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

DMT-2'-O-MOE-rA(Bz) phosphoramidite 화학구조

CAS No. : 251647-53-7

사이즈	재고	수량
무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
250 mg	해외재고보유	Estimated Time of Arrival: December 31
500 mg	해외재고보유	Estimated Time of Arrival: December 31
1 g	해외재고보유	Estimated Time of Arrival: December 31
5 g	해외재고보유	Estimated Time of Arrival: December 31
10 g	견적 받기
50 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of DMT-2'-O-MOE-rA(Bz) phosphoramidite:

DMT-2'-O-MOE-rA(Bz) phosphoramidite (Standard) 견적 받기

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenine nucleoside analog. DMT-2'-O-MOE-rA(Bz) phosphoramidite can be used in research on oligonucleotide synthesis^[1].

In Vitro

In oligonucleotide synthesis, DMT-2'-O-MOE-rA(Bz) phosphoramidite can be used to introduce 2'-O-methoxyethyl-modified adenine into oligonucleotide chains. This modification can enhance the double-strand stability of oligonucleotides, improve their resistance to nucleases, and exhibit relatively low toxicity.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

932.01

화학식

C₅₀H₅₈N₇O₉P

CAS No.

251647-53-7

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=CC=C1)NC2=NC=NC3=C2N=CN3[C@H]4[C@H](OCCOC)[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](COC(C5=CC=C(OC)C=C5)(C6=CC=CC=C6)C7=CC=C(OC)C=C7)O4

선적

Room temperature in continental US; may vary elsewhere.

보관

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

용액&용해도

In Vitro:

DMSO : 200 mg/mL (214.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0729 mL	5.3647 mL	10.7295 mL
5 mM	0.2146 mL	1.0729 mL	2.1459 mL
10 mM	0.1073 mL	0.5365 mL	1.0729 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 98.0%

Select Batch:

Data Sheet (276 KB) SDS (393 KB)

COA (263 KB) HNMR (142 KB)

Handling Instructions (2659 KB)

References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.0729 mL	5.3647 mL	10.7295 mL	26.8237 mL
	5 mM	0.2146 mL	1.0729 mL	2.1459 mL	5.3647 mL
	10 mM	0.1073 mL	0.5365 mL	1.0729 mL	2.6824 mL
	15 mM	0.0715 mL	0.3576 mL	0.7153 mL	1.7882 mL
	20 mM	0.0536 mL	0.2682 mL	0.5365 mL	1.3412 mL
	25 mM	0.0429 mL	0.2146 mL	0.4292 mL	1.0729 mL
	30 mM	0.0358 mL	0.1788 mL	0.3576 mL	0.8941 mL
	40 mM	0.0268 mL	0.1341 mL	0.2682 mL	0.6706 mL
	50 mM	0.0215 mL	0.1073 mL	0.2146 mL	0.5365 mL
	60 mM	0.0179 mL	0.0894 mL	0.1788 mL	0.4471 mL
	80 mM	0.0134 mL	0.0671 mL	0.1341 mL	0.3353 mL
	100 mM	0.0107 mL	0.0536 mL	0.1073 mL	0.2682 mL