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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
106 Results for "
DMT-2
" in MedChemExpress (MCE) Product Catalog:
Products (106)
106 Results for "DMT-2" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-W008662
CAS No.: 146954-74-7
Target:
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2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity .
Synonyms: DMT-2'-O-Methyl-rG(ib) Phosphoramidite
Research Areas:
2'-OMe-G(ibu) Phosphoramidite (DMT-2'-O-Methyl-rG(ib) Phosphoramidite) is a modified phosphoramidite monomer that can be used for the oligonucleotide synthesis .
Cat. No.: HY-45491
CAS No.: 159414-99-0
Synonyms: 2'-F-Ac-dC Phosphoramidite; DMT-2′Fluoro-dC(ac) Phosphoramidite
Research Areas:
Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite) is a phosphoramidite which can be used in the preparation of cyclic purine dinucleotides .
Cat. No.: HY-21997
CAS No.: 136834-22-5
Cat. No.: HY-45409
CAS No.: 146954-75-8
Synonyms: 2'-F-dU Phosphoramidite
Research Areas:
DMT-2’ Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) is a uridine phosphoramidite with a fluorine in the 2’ position. DMT-2’ Fluoro-dU Phosphoramidite could be used for nucleoside modification and synthesis of DNA .
Research Areas:
DMT-2'O-MOE-rG(ib) Phosphoramidite belongs to cyanoethyl-protected nucleoside phosphoramidites. DMT-2'O-MOE-rG(ib) Phosphoramidite is a derivative of nucleotide and guanosine. DMT-2'O-MOE-rG(ib) Phosphoramidite can be used for the stereochemical synthesis of phosphorothioate oligonucleotides .
Cat. No.: HY-45492
CAS No.: 144089-97-4
Synonyms: 2'-F-ibu-dG Phosphoramidite
Research Areas:
DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be employed for oligonucleotide synthesis. DMT-2'Fluoro-DG(IB) Amidite can be used to prepare 4'-modified 2'-deoxy-2'-fluorouridine .
Cat. No.: HY-W006102
CAS No.: 104992-55-4
Synonyms: DMT-2'O-TBDMS-rA(bz) Phosphoramidite
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Bz-rA Phosphoramidite (DMT-2'O-TBDMS-rA(bz) Phosphoramidite) a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis .
Cat. No.: HY-W101391
CAS No.: 110764-79-9
Synonyms: 2'-O-Me-U Phosphoramidite
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DMT-2'O-Methyl-rU Phosphoramidite (2'-O-Me-U Phosphoramidite) is a 2'-O-Me derivative, and can be used for oligonucleotide synthesis [2].
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DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenine nucleoside analog. DMT-2'-O-MOE-rA(Bz) phosphoramidite can be used in research on oligonucleotide synthesis .
Cat. No.: HY-W048482
CAS No.: 118362-03-1
Synonyms: DMT-2'O-TBDMS-rU phosphoramidite
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rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides .
Cat. No.: HY-W784557
CAS No.: 171285-25-9
Research Areas:
O-DMT-2,2-di(ethoxycarbonyl)propan-1,3-diol is a chemical phosphorylation reagent used for the synthesis of 5'-phosphorylated oligonucleotides. It contains the chemical protective group DMT in its structure, which allows for purification through C18 columns or reversed-phase chromatography .
Cat. No.: HY-W093086
CAS No.: 136834-21-4
Cat. No.: HY-W115186
CAS No.: 110764-74-4
Research Areas:
DMT-2'-OMe-Bz-C is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
Cat. No.: HY-W141392
CAS No.: 2245842-16-2
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2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia [2].
Cat. No.: HY-49200
CAS No.: 182495-83-6
Research Areas:
DMT-2'-F-dC(Bz)-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-43059
CAS No.: 81279-39-2
Synonyms: 5'-O-DMT-2'-O-TBDMS-ibu-rG
Research Areas:
5'-O-DMT-2'-O-iBu-N-Bz-Guanosine could be used for silyl protection of ribonucleosides .
Cat. No.: HY-W336559
CAS No.: 166593-57-3
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Research Areas:
5-Me-DMT-2'-O-Me-C(Bz)-CE-Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
Cat. No.: HY-W000665
CAS No.: 123715-02-6
Synonyms: DMT
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Cat. No.: HY-160884
CAS No.: 1470023-72-3
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DMT-2'-OMe-D-Ribitol phosphoramidite is a phosphoramidite monomer synthesized from (2R,3S,4S)-2-hydroxymethyl-4-methoxytetrahydrofuran-3-ol, used to introduce the Y34 abasic moiety into oligonucleotides for solid-phase oligonucleotide synthesis. DMT-2'-OMe-D-Ribitol phosphoramidite can be used for the research of huntington's disease, machado joseph disease (spinocerebellar ataxia 3) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
