2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite

2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite 

Cat. No.: HY-W141392
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2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia.

For research use only. We do not sell to patients.

2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite Chemical Structure

2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite Chemical Structure

CAS No. : 2245842-16-2

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2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite Related Antibodies

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Description

2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia[1][2].

Molecular Weight

772.80

Formula

C40H46FN6O7P
CAS No.
SMILES

COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](F)[C@H](N5C(NC=NC6=O)=C6N=C5)O4
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite2245842-16-2Nucleoside Antimetabolite/Analogpurine oxidaseanti-inflammatoryhypoxia indicatormitochondrial depolarizationInhibitorinhibitorinhibit

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