182495-83-6
Chemical Structure
DMT-2'-F-dC(Bz)-CE-Phosphoramidite
- CAS No.: 182495-83-6
- Formula:C47H53FN5O8P
- Molecular Weight:865.92
IUPAC Name: ((2S,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite
InChIKey: XYPAFCMPDQWTME-LVTIEWELSA-N
SMILES: F[C@@H]1[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](COC(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)C4=CC=C(C=C4)OC)O[C@H]1N5C=C(C)C(NC(C6=CC=CC=C6)=O)=NC5=O
Biological Activity: DMT-2'-F-dC(Bz)-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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DMT-2'-F-dC(Bz)-CE-Phosphoramidite | DMT-2'-F-dC(Bz)-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
