2. Metabolic Enzyme/Protease
  3. Indoleamine 2,3-Dioxygenase (IDO)
  4. DP00477

DP00477 is a potent IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor with an IC50 value of 7.0 µM. DP00477 has the potential for the research of cancer.

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DP00477

DP00477 構造式

CAS 番号 : 169120-56-3

容量 価格（税別） 在庫状況 数量
>無料サンプル (0.1 - 0.2 mg)   今すぐ申し込む  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 143 在庫あり
Solution
10 mM * 1 mL in DMSO USD 143 在庫あり
Solid
5 mg $130 在庫あり
10 mg $220 在庫あり
25 mg $440 在庫あり
50 mg $700 在庫あり
100 mg $1100 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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DP00477 関連抗体

Top Publications Citing Use of Products

Indoleamine 2,3-Dioxygenase (IDO) アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
IDO1 IDO2 IDO

  • 生物活性

  • 純度とドキュメンテーション

  • 参考文献

  • カスタマーレビュー

製品説明

DP00477 is a potent IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor with an IC50 value of 7.0 µM. DP00477 has the potential for the research of cancer[1].

IC50 & Target[1]

IDO1

7.0 μM (IC50)

体外実験

DP00477 inhibits IDO1 activity with IC50s of 71, 6.3 µM when 5 mM GSH or 0.01% Triton-X is added, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DP00477 関連抗体
分子量

397.80

分子式

C17H11ClF3N3OS
CAS 番号
Appearance

Solid

Color

White to light yellow

SMILES

O=C(NC1=CC=CC(C(F)(F)F)=C1)C(C#N)C(NC2=CC=CC=C2Cl)=S
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (251.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5138 mL 12.5691 mL 25.1383 mL
5 mM 0.5028 mL 2.5138 mL 5.0277 mL
10 mM 0.2514 mL 1.2569 mL 2.5138 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 98.21%

COA (246 KB) HNMR (283 KB) RP-HPLC (252 KB) MS (71 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5138 mL 12.5691 mL 25.1383 mL 62.8457 mL
5 mM 0.5028 mL 2.5138 mL 5.0277 mL 12.5691 mL
10 mM 0.2514 mL 1.2569 mL 2.5138 mL 6.2846 mL
15 mM 0.1676 mL 0.8379 mL 1.6759 mL 4.1897 mL
20 mM 0.1257 mL 0.6285 mL 1.2569 mL 3.1423 mL
25 mM 0.1006 mL 0.5028 mL 1.0055 mL 2.5138 mL
30 mM 0.0838 mL 0.4190 mL 0.8379 mL 2.0949 mL
40 mM 0.0628 mL 0.3142 mL 0.6285 mL 1.5711 mL
50 mM 0.0503 mL 0.2514 mL 0.5028 mL 1.2569 mL
60 mM 0.0419 mL 0.2095 mL 0.4190 mL 1.0474 mL
80 mM 0.0314 mL 0.1571 mL 0.3142 mL 0.7856 mL
100 mM 0.0251 mL 0.1257 mL 0.2514 mL 0.6285 mL
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DP00477 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DP00477169120-56-3DP 00477DP-00477Indoleamine 2,3-Dioxygenase (IDO)Inhibitorinhibitorinhibit

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製品名:
DP00477
製品番号:
HY-148383
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