DSPE-PEG5000-Maleimide

Name: DSPE-PEG5000-Maleimide
Brand: MedChemExpress
SKU: HY-140740
Rating: 5.0 (2 reviews)

製品番号: HY-140740 純度: 99.84%: Data Sheet SDS COA 取扱説明書
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DSPE-PEG5000-Maleimide, is a linker lipid containing DSPE phospholipid and Maleimide. DSPE-PEG-Maleimide is used in the synthesis of liposomes, including HELDC liposomes, sterically stabilized liposomes, and immunoliposomes.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量	価格（税別）	在庫状況	数量
>無料サンプル (0.1 - 0.2 mg)		今すぐ申し込む
5 mg	$35	在庫あり	Estimated Time of Arrival: December 31
10 mg	$56	在庫あり	Estimated Time of Arrival: December 31
25 mg	$106	在庫あり	Estimated Time of Arrival: December 31
50 mg	$160	在庫あり	Estimated Time of Arrival: December 31
100 mg	$240	在庫あり	Estimated Time of Arrival: December 31
500 mg	$480	在庫あり	Estimated Time of Arrival: December 31
1 g		お問い合わせ
5 g		お問い合わせ

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カスタマーレビュー

Based on 2 publication(s) in Google Scholar

Other Forms of DSPE-PEG5000-Maleimide:

DSPE-PEG2000-Maleimide sodium (purity>95%) 在庫あり
DSPE-PEG2000-Mal ammonium 在庫あり

顧客検証

Bio/Physico-chemical Assay

: DSPE-PEG5000-Maleimide purchased from MedChemExpress. Usage Cited in: Compos B Eng. 2023 Oct 15, 111047.; The verification of DSPE-PEG2000-MAL-Cys-SDSSD by MALDI-TOF was performed. For the construction of BT-LGG-EVs, 1 mol Cys-SDSSD and 1 mol DSPE-PEG2000-Mal ammonium were mixed and allowed to react for 24 h to develop bone-targeting peptide DSPE-PEG-Mal-Cys-SDSSD.

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参考文献
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製品説明

IC₅₀ & Target

PEGs

体外実験

DSPE-PEG-maleimide can be coupled with thiol-p53_14-29 peptide^[1].
DSPE-PEG-maleimide can be used as a linker lipid in immunoliposome synthesis^[2].
Sterically stabilized liposomes containing DSPE-PEG-maleimide can be coupled with thiolated monoclonal antibody OX26 (OX26-SH)^[2].
HELDC liposomes prepared with 3% DSPE-PEG-maleimide shows no change in particle size over two weeks, with an average diameter of 120 nm^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

5000 (average)

Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCCCCCCCC(O[C@](COP(OCCNC(COCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)(O[Na])=O)([H])COC(CCCCCCCCCCCCCCCCC)=O)=O.[MW 5000].[n]

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : 50 mg/mL (ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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一般には略語で表示されます：C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.84%

Select Batch:

データシート (268 KB) SDS (251 KB)

COA (241 KB) HNMR (274 KB) RP-HPLC (169 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Schnorenberg MR, et, al. Synthesis and Purification of Homogeneous Lipid-Based Peptide Nanocarriers by Overcoming Phospholipid Ester Hydrolysis. ACS Omega. 2018 Oct 31;3(10):14144-14150. [Content Brief]

[2]. Huwyler J, et, al. Brain drug delivery of small molecules using immunoliposomes. Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):14164-9. [Content Brief]

[3]. Wholey WY, et al. Synthetic Liposomal Mimics of Biological Viruses for the Study of Immune Responses to Infection and Vaccination. Bioconjug Chem. 2020 Mar 18;31(3):685-697. [Content Brief]