2. PROTAC
  3. Ligands for E3 Ligase
  4. E3 ligase Ligand 51

E3 ligase Ligand 51 is the ligand for E3 ligase CRBN that can be used for synthesis of PROTAC BTK Degrader-12 (HY-170413).

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E3 ligase Ligand 51

E3 ligase Ligand 51 Estructura química

No. CAS : 2703915-71-1

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E3 ligase Ligand 51 Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1 TRIM21 NEURL1B KLHL41

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Descripciòn

E3 ligase Ligand 51 is the ligand for E3 ligase CRBN that can be used for synthesis of PROTAC BTK Degrader-12 (HY-170413)[1].

IC50 & Target[1]

Cereblon

 

Peso molecular

301.34

Fòrmula

C16H19N3O3
No. CAS
Appearance

Solid

Color

Off-white to light brown

SMILES

O=CC1CCN(C2=CC=C(N(C(N3)=O)CCC3=O)C=C2)CC1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

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Referencias
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E3 ligase Ligand 51 Related Classifications

  • Calculadora de molaridad

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

E3 ligase Ligand 512703915-71-1Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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Nombre del producto:
E3 ligase Ligand 51
Cat. No.:
HY-W245311
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