Elritercept (Synonyms: KER-050)

Cat. No.: HY-P990720 Pureza: 97.868%: Ficha de datos
COA

SDS

FAQs
Technical Support

Elritercept (KER-050) is a recombinant fusion protein comprising a modified activin receptor type IIA extracellular domain fused to a human IgG1 Fc. Elritercept inhibits activin A and other select TGF-β superfamily ligands.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS : 2727114-26-1

Tamaño	Stock	Cantidad
1 mg	En stock	Estimated Time of Arrival: December 31
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
50 mg	Obtener un presupuesto
100 mg	Obtener un presupuesto

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This product is a controlled substance and not for sale in your territory.

Elritercept Recomendaciones destacadas:

Recomendaciones destacadas

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

IC₅₀ & Target

INHBA

Ensayo clínico

Application

ELISA, FACS, Functional assay

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

No. CAS

2727114-26-1

Appearance

Liquid

Color

Colorless to light yellow

Envío

Shipping with dry ice.

Formulation

Please refer to the lot-specific COA for specific buffer information.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Format

FPIA_[PROTEIN]2-FC

Biological Activity

Immobilized Activin A Protein, Human (Biotinylated, HEK293, Avi, HY-P703994) can bind Elritercept. The EC₅₀ for this effect is 9.269 ng/mL.

Pureza y Documentación

Purity: 97.868%

Select Batch:

Ficha de datos (255 KB) SDS (251 KB)

COA (231 KB) SDS-PAGE (66 KB) SEC-HPLC (159 KB)

Inhibitory Antibodies User Guide (603 KB)

Referencias

[1]. Elritercept

[2]. Lachey J, et al. Elritercept, a modified activin receptor IIA ligand trap, increased erythropoiesis and thrombopoiesis in a phase 1 trial. Blood Adv. 2025 Jan 14;9(1):193-201. [Content Brief]

Elritercept Related Classifications

Inflammation/Immunology

Calculadora de molaridad
Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Elritercept2727114-26-1KER-050KER050KER 050TGF-beta/SmadTransforming growth factor betaInhibitorinhibitorinhibit

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