2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. Gentisuric acid

Gentisuric acid, a metabolite of Aspirin (HY-14654), is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C (HY-13316).

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Gentisuric acid

Gentisuric acid Chemical Structure

CAS No. : 25351-24-0

Size Prix Stock Quantité
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
50 mg En stock
100 mg En stock
250 mg En stock
500 mg   Obtenir un devis  
1 g   Obtenir un devis  

* Veuillez sélectionner la quantité avant d'ajouter des articles.

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Other Forms of Gentisuric acid:

Gentisuric acid Related Antibodies

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Description

Gentisuric acid, a metabolite of Aspirin (HY-14654), is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C (HY-13316)[1][2].

Masse moléculaire

211.17

Formule

C9H9NO5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=CC(C(NCC(O)=O)=O)=C(O)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvant et solubilité
In Vitro: 

DMSO : 83.33 mg/mL (394.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7355 mL 23.6776 mL 47.3552 mL
5 mM 0.9471 mL 4.7355 mL 9.4710 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculateur de molarité

  • Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureté et documentation
Références

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.7355 mL 23.6776 mL 47.3552 mL 118.3880 mL
5 mM 0.9471 mL 4.7355 mL 9.4710 mL 23.6776 mL
10 mM 0.4736 mL 2.3678 mL 4.7355 mL 11.8388 mL
15 mM 0.3157 mL 1.5785 mL 3.1570 mL 7.8925 mL
20 mM 0.2368 mL 1.1839 mL 2.3678 mL 5.9194 mL
25 mM 0.1894 mL 0.9471 mL 1.8942 mL 4.7355 mL
30 mM 0.1579 mL 0.7893 mL 1.5785 mL 3.9463 mL
40 mM 0.1184 mL 0.5919 mL 1.1839 mL 2.9597 mL
50 mM 0.0947 mL 0.4736 mL 0.9471 mL 2.3678 mL
60 mM 0.0789 mL 0.3946 mL 0.7893 mL 1.9731 mL
80 mM 0.0592 mL 0.2960 mL 0.5919 mL 1.4799 mL
100 mM 0.0474 mL 0.2368 mL 0.4736 mL 1.1839 mL
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Gentisuric acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gentisuric acid25351-24-0Drug Metaboliteaspirin metabolismα-amidating monooxygenaseDNA-damageInhibitorinhibitorinhibit

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