Gentisuric acid (Standard)
Gentisuric acid (Standard) is the analytical standard of Gentisuric acid (HY-W338852). This product is intended for research and analytical applications. Gentisuric Acid is a metabolite of Aspirin (HY-14654). Gentisuric Acid activates GPR35. Gentisuric Acid inhibits HIF-1α and HIF-2α. Gentisuric Acid inhibits Mitomycin C (HY-13316)-induced genotoxicity and twin spots (mitotic recombination), reduces spot frequency without reducing survival, and modulates replication or repair of Mitomycin C-damaged DNA. Gentisuric Acid can be used in research on VHL-deficient renal cell carcinoma and Drosophila melanogaster infection.
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- Pureté : 98%
- CAS No.: 25351-24-0
- Formule: C9H9NO5
- Masse moléculaire:211.17
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 25351-24-0
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Masse moléculaire 211.17
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Formule C9H9NO5
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SMILES
OC1=CC(C(NCC(O)=O)=O)=C(O)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[4]. Niikawa M, et al. Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2007;61(2-3):113-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Gentisuric acid (Standard)
- 25351-24-0
- Reference Standards
- Drug Metabolite
- GPR35
- HIF/HIF Prolyl-Hydroxylase
- Mitosis
- DNA/RNA Synthesis
- Drosophila melanogaster
- HIF-1α
- HIF-2α
- VHL-defective renal carcinoma
- genotoxicity
- mitomycin C
- mitotic recombination
- renal cell carcinoma
- β-arrestin translocation
- Inhibitor
- inhibitor
- inhibit