25351-24-0
25351-24-0
Chemical Structure
Gentisuric acid
- CAS. Nr.: 25351-24-0
- Formula:C9H9NO5
- Molecular Weight:211.17
IUPAC Name: (2,5-dihydroxybenzoyl)glycine
InChIKey: FBFATOOJCPDQOZ-UHFFFAOYSA-N
SMILES: OC1=CC(C(NCC(O)=O)=O)=C(O)C=C1
Biological Activity: Gentisuric acid, a metabolite of Aspirin (HY-14654), is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C (HY-13316)[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Gentisuric acid | 99.65% | Gentisuric acid, a metabolite of Aspirin (HY-14654), is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C (HY-13316). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Gentisuric acid (Standard) | ≥98% | Gentisuric acid (Standard) is the analytical standard of Gentisuric acid. This product is intended for research and analytical applications. Gentisuric acid, a metabolite of Aspirin (HY-14654), is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C (HY-13316). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. DeBlassio JL, et al. Amidation of salicyluric acid and gentisuric acid: a possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin. Arch Biochem Biophys. 2000 Nov 1;383(1):46-55. [Content Brief]
- [2]. Niikawa M, et al. Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster. Biomed Pharmacother. 2007 Feb-Apr;61(2-3):113-9. [Content Brief]
