2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. KRAS G12C inhibitor 43

KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC50s of 0.001-1 µM, >1 µM, >1 µM for H358, A549, HCC cells ,respectively.

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KRAS G12C inhibitor 43

KRAS G12C inhibitor 43 화학구조

CAS No. : 2648808-69-7

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KRAS G12C inhibitor 43 Related Antibodies

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제품 설명

KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC50s of 0.001-1 µM, >1 µM, >1 µM for H358, A549, HCC cells ,respectively[1].

IC50 & Target[1]

KRas G12C

 

분자량

577.68

화학식

C33H35N7O3
CAS No.
SMILES

C=CC(N1CCN(C[C@@H]1CC#N)C2=C3C=CC(C4=C5C=CC=CC5=CC(OC)=C4)=NC3=NC(OC[C@@H]6CCCN6C)=N2)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

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순도&문서
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KRAS G12C inhibitor 43 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KRAS G12C inhibitor 432648808-69-7Rasantimigrationanti-proliferativeH358A549HCC cellsInhibitorinhibitorinhibit

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상품명:
KRAS G12C inhibitor 43
Cat. No.:
HY-142945
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