L-Asparagine (Standard) (Synonyms: (-)-Asparagine (Standard); Asn (Standard); Asparamide (Standard))

Art. -Nr.: HY-N0667R Reinheit: 99.91%: COA

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L-Asparagine (Standard) is the analytical standard of L-Asparagine (HY-N0667). This product is intended for research and analytical applications. L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

L-Asparagine (Standard) Chemische Struktur

CAS. Nr. : 70-47-3

Größe	Verfügbarkeit	Menge
10 mg	Auf Lager	Estimated Time of Arrival: December 31
25 mg	Auf Lager	Estimated Time of Arrival: December 31
50 mg	Auf Lager	Estimated Time of Arrival: December 31
100 mg	Auf Lager	Estimated Time of Arrival: December 31
200 mg	Angebot einholen
500 mg	Angebot einholen

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Information	L-Asparagine (Standard) is the analytical standard of L-Asparagine (HY-N0667). This product is intended for research and analytical applications. L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
Application	The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molekulargewicht	132.12
Formel	C₄H₈N₂O₃
CAS. Nr.	70-47-3
Appearance	Solid
Color	White to off-white
SMILES	N[C@H](C(O)=O)CC(N)=O
Structure Classification	Amino acids
Initial Source	Endogenous metabolite Disease markers Cancer Endogenous metabolite Disease markers Nervous System Disorder Endogenous metabolite Disease markers Cardiovascular System Disorder Endogenous metabolite Disease markers Immune System Disorder Microorganisms
Versand	Room temperature in continental US; may vary elsewhere.
Speicherung	Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation	Purity: 99.91% Select Batch: SDS (394 KB) COA (146 KB) HNMR (256 KB) RP-HPLC (360 KB) MS (208 KB) Handling Instructions (2659 KB)

L-Asparagine (Standard) Related Classifications

Inflammation/Immunology

Molaritätsrechner
Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Diese Gleichung wird häufig abgekürzt als: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Asparagine (Standard)70-47-3(-)-Asparagine (Standard)Asn (Standard)Asparamide (Standard)Reference StandardsEndogenous MetaboliteApoptosisDNA/RNA SynthesisAsparagine IPEC-J2AntitumorODCInhibitorinhibitorinhibit

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L-Asparagine (Standard) (Synonyms: (-)-Asparagine (Standard); Asn (Standard); Asparamide (Standard))

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Product Information

Reinheit & Dokumentation

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L-Asparagine (Standard) Related Classifications

Molaritätsrechner

Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

The dilution calculator equation

Keywords:

Ihre kürzlich angesehenen Produkte:

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