2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. LBL1

LBL1 is a ligand for lamins (especially lamin A, LA) in the nucleus, that stabilizes the oligomeric state of LA, and affects the assembly state of LA. LBL1 can be used to study the assembly state and dynamic changes of LA.

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LBL1

LBL1 Estructura química

No. CAS : 1605301-58-3

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LBL1 Related Antibodies

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RNASE L DNA Polymerases RNA Polymerases Helicases DNA Ligase

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Descripciòn

LBL1 is a ligand for lamins (especially lamin A, LA) in the nucleus, that stabilizes the oligomeric state of LA, and affects the assembly state of LA. LBL1 can be used to study the assembly state and dynamic changes of LA[1].

Cellular Effect
Cell Line Type Value Description References
MDA-MB-231 GI50
1.6 μM
Compound: 7f
Growth inhibition of human MDA-MB-231 cells after 72 hrs by MTT assay
Growth inhibition of human MDA-MB-231 cells after 72 hrs by MTT assay
[PMID: 24163729]
MDA-MB-468 GI50
0.44 μM
Compound: 7f
Growth inhibition of human MDA-MB-468 cells after 72 hrs by MTT assay
Growth inhibition of human MDA-MB-468 cells after 72 hrs by MTT assay
[PMID: 24163729]
Peso molecular

353.38

Fòrmula

C21H15N5O
No. CAS
SMILES

O=C(C1=CC=C2C=CC=CC2=C1)NC3=NC(N)=C4C5=C(NC=C5)C=CC4=N3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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LBL1 Related Classifications

  • Calculadora de molaridad

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LBL11605301-58-3LBL 1LBL-1DNA/RNA SynthesisassemblyInhibitorinhibitorinhibit

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Nombre del producto:
LBL1
Cat. No.:
HY-115533
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