2. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  3. Opioid Receptor Endogenous Metabolite
  4. [Leu5]-Enkephalin TFA

[Leu5]-Enkephalin TFA is a pentapeptide with morphine like properties. [Leu5]-Enkephalin TFA is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.

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Custom Peptide Synthesis

CAS No. : 73563-78-7

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[Leu5]-Enkephalin TFA Related Antibodies

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    [Leu5]-Enkephalin TFA purchased from MedChemExpress. Usage Cited in: World J Acupunct Moxibustion. 2025 Jun 3.

    [Leu5]-Enkephalin (1-200 μM; 24 h) did not exhibit cytotoxicity in ARPE-19 cells (P > 0.05).

    [Leu5]-Enkephalin TFA purchased from MedChemExpress. Usage Cited in: World J Acupunct Moxibustion. 2025 Jun 3.

    [Leu5]-Enkephalin (10-30 µM; 24 h) significantly ameliorated the OGD-induced reduction in ARPE-19 cell viability.

    [Leu5]-Enkephalin TFA purchased from MedChemExpress. Usage Cited in: World J Acupunct Moxibustion. 2025 Jun 3.

    Impacts of naltrindole and enkephalins treatment on cell viability, morphological changes, and apoptosis rates in OGD/R-injured ARPE-19 cells (mean ± SEM, n = 4 or 5 replicates per group, scale bar = 200 µm). The results showed that following treatment with [Leu5]-Enkephalin (MEK), the cell count increased significantly, and cell morphology reverted to a normal state.

    [Leu5]-Enkephalin TFA purchased from MedChemExpress. Usage Cited in: World J Acupunct Moxibustion. 2025 Jun 3.

    Effects of naloxone and enkephalin on DOR expression in total cellular and membrane protein fractions of ARPE-19 cells under OGD/R (mean ± SEM, n = 4 independent experiments). The results showed that treatment with [Leu5]-Enkephalin (MEK) increased DOR levels in both total proteins (P <0.05) and membrane proteins (P < 0.001).

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    μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

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    Human Endogenous Metabolite Microbial Metabolite

    • Biological Activity

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    제품 설명

    [Leu5]-Enkephalin TFA is a pentapeptide with morphine like properties. [Leu5]-Enkephalin TFA is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.

    IC50 & Target

    Opioid receptors[1]
    분자량

    669.65

    화학식

    C30H38F3N5O9
    CAS No.
    Sequence

    Tyr-Gly-Gly-Phe-Leu
    Sequence Shortening

    YGGFL
    선적

    Room temperature in continental US; may vary elsewhere.
    보관

    Please store the product under the recommended conditions in the Certificate of Analysis.
    순도&문서
    References
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    [Leu5]-Enkephalin TFA Related Classifications

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    Keywords:

    [Leu5]-Enkephalin73563-78-7Opioid ReceptorEndogenous MetaboliteInhibitorinhibitorinhibit

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