1. GPCR/G Protein
    Neuronal Signaling
    Metabolic Enzyme/Protease
  2. Opioid Receptor
    Endogenous Metabolite
  3. [Leu5]-Enkephalin

[Leu5]-Enkephalin (Synonyms: Leu-enkephalin; Leucine enkephalin; Leucyl-enkephalin)

Cat. No.: HY-P0288 Purity: 99.81%
Handling Instructions

[Leu5]-Enkephalin is a pentapeptides with morphine like properties. [Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

[Leu5]-Enkephalin Chemical Structure

[Leu5]-Enkephalin Chemical Structure

CAS No. : 58822-25-6

Size Price Stock Quantity
10 mM * 1 mL in Water USD 66 In-stock
Estimated Time of Arrival: December 31
10 mg USD 60 In-stock
Estimated Time of Arrival: December 31
25 mg USD 120 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

[Leu5]-Enkephalin is a pentapeptides with morphine like properties. [Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Enkephalins (met- , leu-enkephalin, and enkephalin 8) and dynorphins are two classes of opioid peptides found in the spinal dorsal horn. Mu, delta, and kappa are three major subtypes of opioid receptors. Enkephalins are putative endogenous ligands for delta opioid receptors, and dynorphins are endogenous ligands for the kappa opioid receptors. Three receptor types resembling the vertebrate δ- and κ-type opioid receptors have been characterized pharmacologically in nervous tissues (e.g. Ki=18.9 nM for Leu-enkephalin) and localized by autoradiography at CHH terminals in the SG of C. maenas[1].Leucine-enkephalin is a pentapeptides with morphine like properties, naturally present in mammalian brain[2].

Molecular Weight

555.62

Formula

C₂₈H₃₇N₅O₇

CAS No.

58822-25-6

Sequence

Tyr-Gly-Gly-Phe-Leu

Sequence Shortening

YGGFL

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 150 mg/mL (269.97 mM)

H2O : 100 mg/mL (179.98 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7998 mL 8.9990 mL 17.9979 mL
5 mM 0.3600 mL 1.7998 mL 3.5996 mL
10 mM 0.1800 mL 0.8999 mL 1.7998 mL
*Please refer to the solubility information to select the appropriate solvent.
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

[Leu5]-EnkephalinLeu-enkephalinLeucine enkephalinLeucyl-enkephalinOpioid ReceptorEndogenous MetaboliteInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product name:
[Leu5]-Enkephalin
Cat. No.:
HY-P0288
Quantity:
MCE Japan Authorized Agent: