1. GPCR/G Protein
    Neuronal Signaling
  2. Opioid Receptor

Tyr-Gly-Gly-Phe-Met-OH (Synonyms: Met-Enkephalin; Methionine enkephalin)

Cat. No.: HY-P0073 Purity: 99.89%
Handling Instructions

Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.Sequence: Tyr-Gly-Gly-Phe-Met.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Tyr-Gly-Gly-Phe-Met-OH Chemical Structure

Tyr-Gly-Gly-Phe-Met-OH Chemical Structure

CAS No. : 58569-55-4

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
10 mg USD 60 In-stock
Estimated Time of Arrival: December 31
25 mg USD 102 In-stock
Estimated Time of Arrival: December 31
50 mg USD 168 In-stock
Estimated Time of Arrival: December 31
100 mg USD 264 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.Sequence: Tyr-Gly-Gly-Phe-Met.

IC50 & Target

Opioid Receptor[1].

In Vitro

Methionine enkephalin (MENK), an endogenous neuropeptide has a crucial role in both neuroendocrine and immune systems. MENK is believed to have an immunoregulatory activity to have cancer biotherapy activity by binding to the opioid receptors on immune and cancer cells. MENK may also change the tumor microenvironment by binding to opioid receptor on or in cancer cells. All of these mechanisms of action have biologic significance and potential for use in cancer immunotherapy. Furthermore, they reveal a relationship between the endocrine and immune systems[1].

Solvent & Solubility
In Vitro: 

DMSO : ≥ 40 mg/mL (69.73 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7432 mL 8.7160 mL 17.4319 mL
5 mM 0.3486 mL 1.7432 mL 3.4864 mL
10 mM 0.1743 mL 0.8716 mL 1.7432 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

573.66

Formula

C₂₇H₃₅N₅O₇S

CAS No.

58569-55-4

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
Tyr-Gly-Gly-Phe-Met-OH
Cat. No.:
HY-P0073
Quantity:

Tyr-Gly-Gly-Phe-Met-OH

Cat. No.: HY-P0073