1. GPCR/G Protein
    Neuronal Signaling
  2. Opioid Receptor
  3. DPDPE


Cat. No.: HY-P1334 Purity: 98.64%
COA Handling Instructions

DPDPE, an opioid peptide, is a selective δ-opioid receptor (DOR) agonist with anticonvulsant effects.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

DPDPE Chemical Structure

DPDPE Chemical Structure

CAS No. : 88373-73-3

Size Price Stock Quantity
1 mg USD 100 In-stock
Estimated Time of Arrival: December 31
5 mg USD 280 In-stock
Estimated Time of Arrival: December 31
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50 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of DPDPE:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review


DPDPE, an opioid peptide, is a selective δ-opioid receptor (DOR) agonist with anticonvulsant effects[1].

IC50 & Target

δ Opioid Receptor/DOR


In Vivo

DPDPE (70 or 140 nM; i.c.v.; once) shows anticonvulsant effects in rats[1].
DPDPE (0.78–25 μg/mouse; i.c.v.; once) enhances bicuculline-induced convulsions in mouse[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats (225-275 g)[1]
Dosage: 70 or 140 nM followed by a 2 μl saline flush
Administration: Intracerebroventricular injection
Result: Resulted in a significant, dose-dependent increase in the convulsive threshold to flurothyl.
Animal Model: Male ddY mice weighing 20–30 g, pretreated with 1.5 mg/kg bicuculline (subcutaneous injection)[2].
Dosage: 0.78–25 μg/mouse, once
Administration: Intracerebroventricular injection
Result: Caused a dose-dependent increase in the proportion of mice exhibiting convulsions.
Molecular Weight







Tyr-{Pen}-Gly-Phe-{Pen} (Disulfide bridge:Pen2-Pen5)

Sequence Shortening

Y{Pen}GF{Pen} (Disulfide bridge:Pen2-Pen5)


Room temperature in continental US; may vary elsewhere.


Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 10 mg/mL (15.48 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5485 mL 7.7425 mL 15.4849 mL
5 mM 0.3097 mL 1.5485 mL 3.0970 mL
10 mM 0.1548 mL 0.7742 mL 1.5485 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • Dilution Calculator

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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