1. GPCR/G Protein
    Neuronal Signaling
  2. Opioid Receptor
  3. Dynorphin B (1-13)

Dynorphin B (1-13) 

Cat. No.: HY-P1337
Handling Instructions

Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Dynorphin B (1-13) Chemical Structure

Dynorphin B (1-13) Chemical Structure

CAS No. : 83335-41-5

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10 mg USD 680 Get quote

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Other Forms of Dynorphin B (1-13):

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Description

Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.

IC50 & Target

κ-opioid receptor[1]

In Vitro

Dynorphin B (1-13), a 13 amino acid, is an extraordinarily potent opioid peptide. The neurophysiological actions of Dynorphin B (1-13) have been the subject of considerable research effort[1].

Molecular Weight

1570.84

Formula

C₇₄H₁₁₅N₂₁O₁₇

CAS No.

83335-41-5

Sequence

Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr

Sequence Shortening

YGGFLRRQFKVVT

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Dynorphin B (1-13)
Cat. No.:
HY-P1337
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