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  3. Lactoferricin B (4-14), bovine

Lactoferricin B (4-14), bovine  (Synonyms: LfcinB (20–30))

Art. -Nr.: HY-P3917 Reinheit: 99.88%
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LfcinB (20–30) is a fragment of bovine lactoferricin. LfcinB (20–30) has bactericidal, antifungal, antiparasitic, antitumor, antiviral and immunomodulatory activities.

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Kundenspezifische Peptidsynthese

Lactoferricin B (4-14), bovine

Lactoferricin B (4-14), bovine Chemische Struktur

CAS. Nr. : 183476-25-7

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Beschreibung

LfcinB (20–30) is a fragment of bovine lactoferricin. LfcinB (20–30) has bactericidal, antifungal, antiparasitic, antitumor, antiviral and immunomodulatory activities.

In Vitro

LfcinB (20–30) (50 or 100 μg/mL, 24 h) significantly downregulates MMP-1, MMP-3 and MMP-13 at mRNA and protein levels in a concentration-dependent manner in chondrocyte[1].
LfcinB (20–30) (50 μg/mL, 24 h) can effectively activate ERK MAPK and Akt pathways, thus mediating anti-inflammatory effects[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

1544.87

Formel

C70H113N25O13S

CAS. Nr.
Appearance

Solid

Color

White to off-white

Sequence

Arg-Arg-Trp-Gln-Trp-Arg-Met-Lys-Lys-Leu-Gly

Sequence Shortening

RRWQWRMKKLG

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 20 mg/mL (12.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6473 mL 3.2365 mL 6.4730 mL
5 mM 0.1295 mL 0.6473 mL 1.2946 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation
Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6473 mL 3.2365 mL 6.4730 mL 16.1826 mL
5 mM 0.1295 mL 0.6473 mL 1.2946 mL 3.2365 mL
10 mM 0.0647 mL 0.3237 mL 0.6473 mL 1.6183 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Produktname:
Lactoferricin B (4-14), bovine
Art. -Nr.:
HY-P3917
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