Nifedipine hydrochloride

製品番号: HY-B0284A: Data Sheet 取扱説明書
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Nifedipine hydrochloride is a potent vasodilator with calcium antagonist activity. Nifedipine hydrochloride is a useful antianginal compound that can also lower blood pressure. Nifedipine hydrochloride exhibits comparable antihypertensive properties to some new compounds, especially in calcium channel blockade. Nifedipine hydrochloride is used in biological activity studies to develop new antihypertensive and/or antianginal compounds.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号 : 60299-11-8

容量		在庫状況
MOQ		Minimum order quantity
50 mg		お問い合わせ
100 mg		お問い合わせ
250 mg		お問い合わせ
Other size		お問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

Other 在庫あり Forms of Nifedipine hydrochloride:

Nifedipine

Other Forms of Nifedipine hydrochloride:

Nifedipine 在庫あり
Nifedipine-d₆ お問い合わせ
Nifedipine-d₄ お問い合わせ
Nifedipine-¹³C₈ お問い合わせ

顧客検証

Cell Imaging/Staining

Others

Bio/Physico-chemical Assay

: Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Alzheimers Res Ther. 2025 Dec 1;17(1):253. [Abstract]; Nifedipine (5 µM, 1 min) decreased the neuronal cytoplasmic Ca²⁺ levels induced by 20 µM glutamate.

: Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Pharmaceuticals (Basel). 2025 Sep 21;18(9):1420. [Abstract]; Nifedipine (0.01 µM, 30 min) inhibited contractions induced by Ca²⁺ influx, keeping the contraction force below 0.1 g even at the highest calcium concentration of 10 mM.

: Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Sci Signal. 2020 Nov 24;13(659):eaax0273. [Abstract]; Nifedipine (10 µM, 30 min) relaxed 0.3 μM ACh-constricted mouse airways.

: Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Sci Signal. 2020 Nov 24;13(659):eaax0273. [Abstract]; Pretreatment with nifedipine (10 µM, 30 min) reduced ACh-induced airway constriction by about 25% but did not affect osthole-induced relaxation in mouse airways.

: Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Front Endocrinol. 2018 Nov 30:9:721. [Abstract]; Nifedipine (4 µM, 4 h) abolished the stimulation of Gh release by GnRH1 or GnRH3 in primary cultured pituitary cells from mixed-sex rice field eels.

Sodium Channel アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Na_v1.1 Na_v1.2 Na_v1.3 Na_v1.4 Na_v1.5 Na_v1.6 Na_v1.7 Na_v1.8 Na_v1.9

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明	Nifedipine hydrochloride is a potent vasodilator with calcium antagonist activity. Nifedipine hydrochloride is a useful antianginal compound that can also lower blood pressure. Nifedipine hydrochloride exhibits comparable antihypertensive properties to some new compounds, especially in calcium channel blockade. Nifedipine hydrochloride is used in biological activity studies to develop new antihypertensive and/or antianginal compounds^[1].
分子量	382.80
分子式	C₁₇H₁₉ClN₂O₆
CAS 番号	60299-11-8
SMILES	O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC=C2[N+]([O-])=O)OC.Cl
輸送条件	Room temperature in continental US; may vary elsewhere.
保管条件	Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション	データシート (273 KB) 取扱説明書 (2659 KB)
参考文献	[1]. Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Pyrimidine Derivatives as Potential Calcium Channel Blockers [Content Brief]