O-Desmethyltramadol-d₆ hydrochloride

Art. -Nr.: HY-109054AS: Data Sheet Handling Instructions
FAQs
Technical Support

O-Desmethyltramadol-d6 hydrochloride is a deuterated labeled O-Desmethyltramadol hydrochloride. O-Desmethyltramadol hydrochloride is the main active metabolite of tramadol (Tramadol) and can cross the blood-brain barrier. O-Desmethyltramadol hydrochloride mainly exerts its analgesic effect by activating the µ-opioid receptor (µ-OR).

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

O-Desmethyltramadol-d<sub>6</sub> hydrochloride

O-Desmethyltramadol-d₆ hydrochloride Chemische Struktur

CAS. Nr. : 1261393-87-6

Größe	Verfügbarkeit	Menge
1 mg	Angebot einholen 3 - 4 weeks 5 - 7 weeks 6 - 8 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
5 mg	Angebot einholen
10 mg	Angebot einholen

Synthetic products have potential research and development risk.

or Massenanfrage

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

This product is a controlled substance and not for sale in your territory.

Other Forms of O-Desmethyltramadol-d₆ hydrochloride:

O-Desmethyltramadol hydrochloride In-stock

Spezialitätsempfehlungen

•Related Small Molecules:

•Related Proteins:

Alle Opioid Receptor Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen

μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

Biologische Aktivität
Reinheit & Dokumentation
Verweise
Kundenbewertung

Beschreibung	O-Desmethyltramadol-d6 hydrochloride is a deuterated labeled O-Desmethyltramadol hydrochloride. O-Desmethyltramadol hydrochloride is the main active metabolite of tramadol (Tramadol) and can cross the blood-brain barrier. O-Desmethyltramadol hydrochloride mainly exerts its analgesic effect by activating the µ-opioid receptor (µ-OR)^[1]^[2]^[3].
Application	1. This compound can be used as a tracer. 2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. O-Desmethyltramadol-d₆ hydrochloride Related Antibodies
Molekulargewicht	291.85
Formel	C₁₅H₁₈D₆ClNO₂
CAS. Nr.	1261393-87-6
Unlabeled CAS	185453-02-5
SMILES	O[C@@]1(C2=CC(O)=CC=C2)[C@H](CCCC1)CN(C([2H])([2H])[2H])C([2H])([2H])[2H].Cl
Versand	Room temperature in continental US; may vary elsewhere.
Speicherung	Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation	Data Sheet (270 KB) Handling Instructions (2659 KB)
Verweise	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief] [2]. Lee J, et al. Population pharmacokinetic analysis of tramadol and O-desmethyltramadol with genetic polymorphism of CYP2D6. Drug Des Devel Ther. 2019;13:1751-1761. [Content Brief] [3]. Liu HC, et al. Transportation of the enantiomers of trans tramadol and O-demethyltramadol across blood-brain barrier. Yao Xue Xue Bao. 2001 Sep;36(9):644-7. Chinese. [Content Brief]