1. Immunology/Inflammation
  2. CD3
  3. Obertamig

Obertamig is an engineered, humanized, anti-CD3E/HLA-G monoclonal antibody with humanized CH2-CH3 modifications and consists of half immunoglobulin IgG1 λ2 and a single-chain variable fragment (scFv).

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No. CAS : 2750126-32-8

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Descripciòn

Obertamig is an engineered, humanized, anti-CD3E/HLA-G monoclonal antibody with humanized CH2-CH3 modifications and consists of half immunoglobulin IgG1 λ2 and a single-chain variable fragment (scFv)[1].

Isotype

Human IgG1 kappa

Recommend Isotype Controls
Species Reactivity

Human

IC50 & Target

CD3E & HLA-G

Gene ID

916  [NCBI] & 3135  [NCBI]

Accession
Application

ELISA, FACS, Functional assay

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Peso molecular

148.813 kDa

No. CAS
Appearance

Liquid

Color

Colorless to light yellow

Envío

Shipping with dry ice.

Formulation

Please refer to the lot-specific COA for specific buffer information.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • IgG1-kappa
Biological Activity
  • Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Obertamig. The EC50 for this effect is 475.8 ng/mL.
  • Immobilized HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein, Human (HEK293, His-Avi, HY-P77690) can bind Obertamig. The EC50 for this effect is 299.9 ng/mL.
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Referencias
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  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Obertamig
Cat. No.:
HY-P990714
Cantidad:
MCE Japan Authorized Agent: