2. Anti-infection
  3. Bacterial
  4. Oligopeptide-10

Oligopeptide-10 is a bioactive peptide with antimicrobial activity. Oligopeptide-10 exhibits broad-spectrum bactericidal effects against Gram-positive bacteria including Propionibacterium acnes and Staphylococcus aureus. Oligopeptide-10 targets lipoteichoic acid (LTA) on the surface of bacterial cell membranes, induces bacterial osmotic imbalance by disrupting the integrity of bacterial membranes, and reduces the release of pro-inflammatory cytokines induced by bacteria. Oligopeptide-10 possesses skin-protective activity. Oligopeptide-10 can be applied in research related to acne vulgaris, dandruff, seborrheic dermatitis, and tinea pedis.

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Oligopeptide-10

Oligopeptide-10 構造式

CAS 番号 : 466691-40-7

容量 価格（税別） 在庫状況 数量
5 mg $50 在庫あり
10 mg $80 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Oligopeptide-10 関連抗体

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製品説明

Oligopeptide-10 is a bioactive peptide with antimicrobial activity. Oligopeptide-10 exhibits broad-spectrum bactericidal effects against Gram-positive bacteria including Propionibacterium acnes and Staphylococcus aureus. Oligopeptide-10 targets lipoteichoic acid (LTA) on the surface of bacterial cell membranes, induces bacterial osmotic imbalance by disrupting the integrity of bacterial membranes, and reduces the release of pro-inflammatory cytokines induced by bacteria. Oligopeptide-10 possesses skin-protective activity. Oligopeptide-10 can be applied in research related to acne vulgaris, dandruff, seborrheic dermatitis, and tinea pedis[1][2][3].

体外実験

Oligopeptide-10 exhibits broad-spectrum bactericidal effects against Gram-positive bacteria including Propionibacterium acnes and Staphylococcus aureus[1][3].
Oligopeptide-10 exhibits no cytotoxicity, irritation, sensitization, or mutagenicity in in vitro safety evaluations[1].
Oligopeptide-10 binds to lipoteichoic acid (LTA) on the bacterial surface, exerts antimicrobial activity, neutralizes pro-inflammatory bacterial components and reduces inflammatory responses[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Oligopeptide-10 関連抗体
分子量

1598.07

分子式

C78H140N20O15
CAS 番号
Appearance

Solid

Color

White to off-white

Sequence

Phe-Ala-Lys-Ala-Leu-Lys-Ala-Leu-Leu-Lys-Ala-Leu-Lys-Ala-Leu-NH2
Sequence Shortening

FAKALKALLKALKAL-NH2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Sealed storage, away from moisture
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (62.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6258 mL 3.1288 mL 6.2575 mL
5 mM 0.1252 mL 0.6258 mL 1.2515 mL
10 mM 0.0626 mL 0.3129 mL 0.6258 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6258 mL 3.1288 mL 6.2575 mL 15.6439 mL
5 mM 0.1252 mL 0.6258 mL 1.2515 mL 3.1288 mL
10 mM 0.0626 mL 0.3129 mL 0.6258 mL 1.5644 mL
15 mM 0.0417 mL 0.2086 mL 0.4172 mL 1.0429 mL
20 mM 0.0313 mL 0.1564 mL 0.3129 mL 0.7822 mL
25 mM 0.0250 mL 0.1252 mL 0.2503 mL 0.6258 mL
30 mM 0.0209 mL 0.1043 mL 0.2086 mL 0.5215 mL
40 mM 0.0156 mL 0.0782 mL 0.1564 mL 0.3911 mL
50 mM 0.0125 mL 0.0626 mL 0.1252 mL 0.3129 mL
60 mM 0.0104 mL 0.0521 mL 0.1043 mL 0.2607 mL
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Oligopeptide-10 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Oligopeptide-10466691-40-7Oligopeptide10Oligopeptide 10Bacterialbacterial cell deathacne vulgarisinnate immunity peptide templateCutibacterium acnespro-inflammatory bacterial componentsdandrufflipoteichoic acidseborrheic dermatitistinea pedisInhibitorinhibitorinhibit

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製品名:
Oligopeptide-10
製品番号:
HY-P5255
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