466691-40-7
Chemical Structure
Oligopeptide-10
- CAS No.: 466691-40-7
- Formula:C78H140N20O15
- Molecular Weight:1598.07
InChIKey: XWZAWHJNTHSHGD-SIDOVBMKSA-N
SMILES: O=C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC1=CC=CC=C1)N
Biological Activity: Oligopeptide-10 is a bioactive peptide with antimicrobial activity. Oligopeptide-10 exhibits broad-spectrum bactericidal effects against Gram-positive bacteria including Propionibacterium acnes and Staphylococcus aureus. Oligopeptide-10 targets lipoteichoic acid (LTA) on the surface of bacterial cell membranes, induces bacterial osmotic imbalance by disrupting the integrity of bacterial membranes, and reduces the release of pro-inflammatory cytokines induced by bacteria. Oligopeptide-10 possesses skin-protective activity. Oligopeptide-10 can be applied in research related to acne vulgaris, dandruff, seborrheic dermatitis, and tinea pedis[1][2][3].
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Oligopeptide-10 | 99.91% | Oligopeptide-10 is a bioactive peptide with antimicrobial activity. Oligopeptide-10 exhibits broad-spectrum bactericidal effects against Gram-positive bacteria including Propionibacterium acnes and Staphylococcus aureus. Oligopeptide-10 targets lipoteichoic acid (LTA) on the surface of bacterial cell membranes, induces bacterial osmotic imbalance by disrupting the integrity of bacterial membranes, and reduces the release of pro-inflammatory cytokines induced by bacteria. Oligopeptide-10 possesses skin-protective activity. Oligopeptide-10 can be applied in research related to acne vulgaris, dandruff, seborrheic dermatitis, and tinea pedis. | ||||||||||||||||||||
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References
- [1]. Avcil M. Efficacy of Dissolvable Microneedle Patches with Skincare Actives in Acne Management: A Monocentric Clinical Study. Biologics. 2025;5(2):15.
- [2]. Fields K. Bioactive peptides: signaling the future. J Cosmet Dermatol. 2009;8(1):8-13.
- [3]. Zhang L. Cosmeceuticals and peptides. Clin Dermatol. 2009;27(5):485-494.
