2. Metabolic Enzyme/Protease Stem Cell/Wnt JAK/STAT Signaling Apoptosis
  3. Pyruvate Kinase STAT Apoptosis
  4. PKM2 activator 11

PKM2 activator 11 (Compound 23) is a PKM2 activator with an AC50 value of 92.12 nM. PKM2 activator 11 promotes PKM2 tetramerization and inhibits its nuclear translocation. PKM2 activator 11 suppresses glycolysis and the PKM2/STAT3 signaling pathway. PKM2 activator 11 induces Apoptosis. PKM2 activator 11 exhibits anti-CRC activity in vitro with potency and selectivity.

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PKM2 activator 11

PKM2 activator 11 Estructura química

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PKM2 activator 11 Related Antibodies

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Descripciòn

PKM2 activator 11 (Compound 23) is a PKM2 activator with an AC50 value of 92.12 nM. PKM2 activator 11 promotes PKM2 tetramerization and inhibits its nuclear translocation. PKM2 activator 11 suppresses glycolysis and the PKM2/STAT3 signaling pathway. PKM2 activator 11 induces Apoptosis. PKM2 activator 11 exhibits anti-CRC activity in vitro with potency and selectivity[1].

IC50 & Target[1]

STAT3

 

PKM2

 

Peso molecular

457.54

Fòrmula

C27H23NO4S
SMILES

O=C(C1=O)C2=C(OC(CN3CCC(SC=C4)=C4C3)=C2C)C5=C1C6=C(C=C5)C(C)(C)C(C=C6)=O
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PKM2 activator 11 Related Classifications

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Keywords:

PKM2 activator 11Pyruvate KinaseSTATApoptosisanti-CRCInhibitorinhibitorinhibit

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PKM2 activator 11
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