1. GPCR/G Protein Metabolic Enzyme/Protease
  2. GPR84 Aldose Reductase
  3. Pyrone-211

Pyrone-211 is a potent GPR84 agonist and AKR1C3 inhibitor. Pyrone-211 participates in an expanded polyamine pathway.

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Pyrone-211

Pyrone-211 構造式

CAS 番号 : 90632-45-4

容量 価格(税別) 在庫状況 数量
5 mg $780 在庫あり
10 mg $1250 在庫あり
25 mg $2000 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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  • 生物活性

  • 純度とドキュメンテーション

  • 参考文献

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製品説明

Pyrone-211 is a potent GPR84 agonist and AKR1C3 inhibitor. Pyrone-211 participates in an expanded polyamine pathway[1].

分子量

210.27

分子式

C12H18O3

CAS 番号
Appearance

Solid

Color

White to light yellow

SMILES

O=C1OC(CCCCCCC)=CC(O)=C1

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶剤 & 溶解度
体外: 

DMSO : ≥ 100 mg/mL (475.58 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7558 mL 23.7789 mL 47.5579 mL
5 mM 0.9512 mL 4.7558 mL 9.5116 mL
10 mM 0.4756 mL 2.3779 mL 4.7558 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始)

C1

×
体積 (開始)

V1

=
濃度 (終了)

C2

×
体積 (終了)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.7558 mL 23.7790 mL 47.5579 mL 118.8948 mL
5 mM 0.9512 mL 4.7558 mL 9.5116 mL 23.7790 mL
10 mM 0.4756 mL 2.3779 mL 4.7558 mL 11.8895 mL
15 mM 0.3171 mL 1.5853 mL 3.1705 mL 7.9263 mL
20 mM 0.2378 mL 1.1889 mL 2.3779 mL 5.9447 mL
25 mM 0.1902 mL 0.9512 mL 1.9023 mL 4.7558 mL
30 mM 0.1585 mL 0.7926 mL 1.5853 mL 3.9632 mL
40 mM 0.1189 mL 0.5945 mL 1.1889 mL 2.9724 mL
50 mM 0.0951 mL 0.4756 mL 0.9512 mL 2.3779 mL
60 mM 0.0793 mL 0.3963 mL 0.7926 mL 1.9816 mL
80 mM 0.0594 mL 0.2972 mL 0.5945 mL 1.4862 mL
100 mM 0.0476 mL 0.2378 mL 0.4756 mL 1.1889 mL
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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備考

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Inquiry Information

製品名:
Pyrone-211
製品番号:
HY-171115
数量:
MCE 日本正規代理店: