2. Metabolic Enzyme/Protease
  3. Angiotensin-converting Enzyme (ACE)
  4. (R)-MLN-4760

(R)-MLN-4760, the R-enantiomer of MLN-4760, is an ACE2 inhibitor, with an IC50 of 8.4 μM. (R)-MLN-4760 is the less active isomer.

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(R)-MLN-4760

(R)-MLN-4760 화학구조

CAS No. : 305335-29-9

사이즈 가격 재고 수량
무료 샘플 (0.1 - 0.2 mg)   지금 신청하기  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

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고객리뷰

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Other Forms of (R)-MLN-4760:

(R)-MLN-4760 Related Antibodies

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제품 설명

(R)-MLN-4760, the R-enantiomer of MLN-4760, is an ACE2 inhibitor, with an IC50 of 8.4 μM. (R)-MLN-4760 is the less active isomer[1].

IC50 & Target

IC50: 8.4 nM (ACE2)[1]
In Vitro

(R)-MLN-4760 (compound 16RS) is the less active isomer of MLN-4760[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(R)-MLN-4760 Related Antibodies
분자량

428.31

화학식

C19H23Cl2N3O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)[C@H](CC1=CN=CN1CC2=CC(Cl)=CC(Cl)=C2)N[C@@H](C(O)=O)CC(C)C
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
용액&용해도
In Vitro: 

DMSO : 14.29 mg/mL (33.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3348 mL 11.6738 mL 23.3476 mL
5 mM 0.4670 mL 2.3348 mL 4.6695 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3348 mL 11.6738 mL 23.3476 mL 58.3689 mL
5 mM 0.4670 mL 2.3348 mL 4.6695 mL 11.6738 mL
10 mM 0.2335 mL 1.1674 mL 2.3348 mL 5.8369 mL
15 mM 0.1557 mL 0.7783 mL 1.5565 mL 3.8913 mL
20 mM 0.1167 mL 0.5837 mL 1.1674 mL 2.9184 mL
25 mM 0.0934 mL 0.4670 mL 0.9339 mL 2.3348 mL
30 mM 0.0778 mL 0.3891 mL 0.7783 mL 1.9456 mL
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(R)-MLN-4760 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-MLN-4760305335-29-9Angiotensin-converting Enzyme (ACE)ACE2ACECPDAInhibitorinhibitorinhibit

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Inquiry Information

상품명:
(R)-MLN-4760
Cat. No.:
HY-19414A
수량:
MCE Japan Authorized Agent:

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