1. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  2. Reactive Oxygen Species (ROS)
  3. ROS-IN-1

ROS-IN-1 is a mitochondrial ROS inhibitor. ROS-IN-1 can reduce oxidative stress or inhibit reactive oxygen species (ROS) production.

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ROS-IN-1

ROS-IN-1 Chemische Struktur

CAS. Nr. : 298193-11-0

Größe Preis Verfügbarkeit Menge
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
Auf Lager
Solution
10 mM * 1 mL in DMSO Auf Lager
Solid
5 mg Auf Lager
10 mg Auf Lager
50 mg   Angebot einholen  
100 mg   Angebot einholen  

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Beschreibung

ROS-IN-1 is a mitochondrial ROS inhibitor. ROS-IN-1 can reduce oxidative stress or inhibit reactive oxygen species (ROS) production[1].

In Vitro

ROS-IN-1 (Compound 40) can reduce ROS production (25.1%)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

267.34

Formel

C13H17NO3S

CAS. Nr.
Appearance

Solid

Color

White to off-white

SMILES

O=C1N(S(=O)(C2=C(C)C=C(C)C=C2C)=O)CCC1

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 100 mg/mL (374.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7406 mL 18.7028 mL 37.4056 mL
5 mM 0.7481 mL 3.7406 mL 7.4811 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation

Purity: 99.14%

Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7406 mL 18.7028 mL 37.4056 mL 93.5139 mL
5 mM 0.7481 mL 3.7406 mL 7.4811 mL 18.7028 mL
10 mM 0.3741 mL 1.8703 mL 3.7406 mL 9.3514 mL
15 mM 0.2494 mL 1.2469 mL 2.4937 mL 6.2343 mL
20 mM 0.1870 mL 0.9351 mL 1.8703 mL 4.6757 mL
25 mM 0.1496 mL 0.7481 mL 1.4962 mL 3.7406 mL
30 mM 0.1247 mL 0.6234 mL 1.2469 mL 3.1171 mL
40 mM 0.0935 mL 0.4676 mL 0.9351 mL 2.3378 mL
50 mM 0.0748 mL 0.3741 mL 0.7481 mL 1.8703 mL
60 mM 0.0623 mL 0.3117 mL 0.6234 mL 1.5586 mL
80 mM 0.0468 mL 0.2338 mL 0.4676 mL 1.1689 mL
100 mM 0.0374 mL 0.1870 mL 0.3741 mL 0.9351 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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