1. GPCR/G Protein
  2. Bradykinin Receptor
  3. Sar-[D-Phe8]-des-Arg9-Bradykinin

Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings.

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Sar-[D-Phe8]-des-Arg9-Bradykinin

Sar-[D-Phe8]-des-Arg9-Bradykinin Chemische Struktur

CAS. Nr. : 126959-88-4

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
Auf Lager
Solution
10 mM * 1 mL in DMSO Auf Lager
Solid
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Beschreibung

Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings[1].

Molekulargewicht

975.10

Formel

C47H66N12O11

CAS. Nr.
Appearance

Solid

Color

White to off-white

Sequence

{Sar}-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe

Sequence Shortening

{Sar}-RPPGFSPF

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 100 mg/mL (102.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0255 mL 5.1277 mL 10.2554 mL
5 mM 0.2051 mL 1.0255 mL 2.0511 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation

Purity: 99.96%

Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.0255 mL 5.1277 mL 10.2554 mL 25.6384 mL
5 mM 0.2051 mL 1.0255 mL 2.0511 mL 5.1277 mL
10 mM 0.1026 mL 0.5128 mL 1.0255 mL 2.5638 mL
15 mM 0.0684 mL 0.3418 mL 0.6837 mL 1.7092 mL
20 mM 0.0513 mL 0.2564 mL 0.5128 mL 1.2819 mL
25 mM 0.0410 mL 0.2051 mL 0.4102 mL 1.0255 mL
30 mM 0.0342 mL 0.1709 mL 0.3418 mL 0.8546 mL
40 mM 0.0256 mL 0.1282 mL 0.2564 mL 0.6410 mL
50 mM 0.0205 mL 0.1026 mL 0.2051 mL 0.5128 mL
60 mM 0.0171 mL 0.0855 mL 0.1709 mL 0.4273 mL
80 mM 0.0128 mL 0.0641 mL 0.1282 mL 0.3205 mL
100 mM 0.0103 mL 0.0513 mL 0.1026 mL 0.2564 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Sar-[D-Phe8]-des-Arg9-Bradykinin
Art. -Nr.:
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