2. Signaling Pathways
  3. GPCR/G Protein
  4. Bradykinin Receptor
  5. Bradykinin B2 Receptor (B2R) Isoform

Bradykinin B2 Receptor (B2R)

 

Bradykinin B2 Receptor (B2R) Related Products (6):

Cat. No. Product Name Effect Purity
  • HY-P0206
    Bradykinin
    		Modulator 99.86%
    Bradykinin is an active peptide that is generated by the kallikrein-kinin system. It is a inflammatory mediator and also recognized as a neuromediator and regulator of several vascular and renal functions.
  • HY-17446
    Icatibant
    		Antagonist 99.51%
    Icatibant (HOE-140) is a potent and specific peptide antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively.
  • HY-105155
    Lobradimil
    		Agonist 99.51%
    Lobradimil (RMP 7), a synthetic bradykinin analog, is a potent and selective bradykinin B2 receptor agonist (Ki: 0.54 nM). Lobradimil increases the permeability of the BBB. Lobradimil can be used in the research of brain tumors.
  • HY-106277
    Fasitibant free base
    		Antagonist
    Fasitibant (free base) is a potent, selective, high affinity, and long-lasting nonpeptide bradykinin B2 (BK2) receptor antagonist. Fasitibant (free base) has proinflammatory effects and can be used for the research of osteoarthritis and rheumatoid arthritis.
  • HY-P3232
    B 9430
    		Antagonist
    B 9430 is a potent bradykinin B1/B2 receptor antagonist.
  • HY-106277A
    Fasitibant chloride hydrochloride
    		Antagonist
    Fasitibant chloride hydrochloride (MEN16132) is a potent, selective, high affinity, and long-lasting nonpeptide bradykinin B2 (BK2) receptor antagonist. Fasitibant chloride hydrochloride has proinflammatory effects and can be used for the research of osteoarthritis and rheumatoid arthritis.