159768-75-9
Chemical Structure
Lobradimil
Synonym(s): RMP 7
- CAS No.: 159768-75-9
- Formula:C49H75N15O12S
- Molecular Weight:1098.28
IUPAC Name: ((S)-2-((S)-1-(((S)-2-(2-((2S,4R)-1-(L-arginyl-L-prolyl)-4-hydroxypyrrolidine-2-carboxamido)acetamido)-3-(thiophen-2-yl)propanoyl)-L-seryl)pyrrolidine-2-carboxamido)-3-(4-methoxyphenyl)propyl)-L-arginine
InChIKey: IDXCXSCCZNCXCL-XMADEQCMSA-N
SMILES: O=C([C@H]1N(CCC1)C([C@@H](N)CCCNC(N)=N)=O)N2[C@@H](C[C@H](C2)O)C(NCC(N[C@H](C(N[C@@H](CO)C(N3[C@@H](CCC3)C(N[C@H](CN[C@H](C(O)=O)CCCNC(N)=N)CC4=CC=C(C=C4)OC)=O)=O)=O)CC5=CC=CS5)=O)=O
Biological Activity: Lobradimil (RMP 7), a synthetic bradykinin analog, is a potent and selective bradykinin B2 receptor agonist (Ki: 0.54 nM). Lobradimil increases the permeability of the BBB. Lobradimil can be used in the research of brain tumors[1].
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Lobradimil | 99.76% | Lobradimil (RMP 7), a synthetic bradykinin analog, is a potent and selective bradykinin B2 receptor agonist (Ki: 0.54 nM). Lobradimil increases the permeability of the BBB. Lobradimil can be used in the research of brain tumors. | ||||||||||||||||||||
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Keywords
