2. GPCR/G Protein
  3. Bradykinin Receptor
  4. WIN 64338

WIN 64338 is a non-peptide bradykinin B2 receptor antagonist. WIN 64338 can inhibit bradykinin-evoked trigeminal nerve stimulation.

For research use only. We do not sell to patients.

WIN 64338

WIN 64338 Chemical Structure

CAS No. : 151039-63-3

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Other Forms of WIN 64338:

WIN 64338 Related Antibodies

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Bradykinin B1 Receptor (B1R) Bradykinin B2 Receptor (B2R)

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Description

WIN 64338 is a non-peptide bradykinin B2 receptor antagonist. WIN 64338 can inhibit bradykinin-evoked trigeminal nerve stimulation[1].

IC50 & Target[1]

Bradykinin B2 Receptor (B2R)

 

In Vitro

WIN 64338 (1-10 μM, 30 mins) competitively antagonizes bradykinin-evoked contractile responses in isolated rabbit iris sphincter with a pKB of 6.6[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

WIN 64338 Related Antibodies
In Vivo

WIN 64338 (30-300 nmol/kg, i.v., 15 min before bradykinin administration) inhibits bradykinin-induced conjunctival and nasal mucosa plasma extravasation in guinea pigs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

747.47

Formula

C45H68ClN4OP
CAS No.
SMILES

O=C(NC1=CC=C(C[P+](CCCC)(CCCC)CCCC)C=C1)[C@@H](/N=C(NC2CCCCC2)/NC3CCCCC3)CC4=CC=C5C=CC=CC5=C4.[Cl-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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WIN 64338 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WIN 64338151039-63-3WIN64338WIN-64338Bradykinin ReceptorBradykinin B2 receptorbradykinintrigeminal nerveInhibitorinhibitorinhibit

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