215258-13-2
Chemical Structure
FR167344 free base
- CAS No.: 215258-13-2
- Formula:C30H28BrCl2N5O4
- Molecular Weight:673.38
IUPAC Name: (E)-4-(3-((2-((3-(((3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxy)methyl)-2,4-dichlorophenyl)(methyl)amino)-2-oxoethyl)amino)-3-oxoprop-1-en-1-yl)-N,N-dimethylbenzamide
InChIKey: NDOBHDUXUJNXHX-NTEUORMPSA-N
SMILES: O=C(N(C)C)C1=CC=C(/C=C/C(NCC(N(C2=CC=C(Cl)C(COC3=CC=CN4C3=NC(C)=C4Br)=C2Cl)C)=O)=O)C=C1
Biological Activity: FR167344 free base is an orally active, nonpeptide bradykinin receptor B2 antagonist. FR167344 free base shows a high affinity binding to the B2 receptor with an IC50 value of 65 nM and no binding affinity for the B1 receptor.
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FR167344 free base | FR167344 free base is an orally active, nonpeptide bradykinin receptor B2 antagonist. FR167344 free base shows a high affinity binding to the B2 receptor with an IC50 value of 65 nM and no binding affinity for the B1 receptor. | |||||||||||||||||||||
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Keywords
