1. GPCR/G Protein
  2. GPR40
  3. SCO-267

SCO-267 

Cat. No.: HY-132265
Handling Instructions

SCO-267 is an allosteric GPR40 full agonist. SCO-267 can be used for the research of chronic diseases including diabetes.

For research use only. We do not sell to patients.

SCO-267 Chemical Structure

SCO-267 Chemical Structure

CAS No. : 1656261-09-4

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Description

SCO-267 is an allosteric GPR40 full agonist. SCO-267 can be used for the research of chronic diseases including diabetes[1].

IC50 & Target

GPR40[1]

In Vitro

SCO-267 (CHO cells) activates the Gαq, Gαs, and Gα12/13 pathways and β-Arrestin Recruitment. SCO-267 is allosteric with fasiglifam and an endogenous ligand[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

SCO-267 (1 or 10 mg/kg; p.o.) improves insulin sensitivity and exerts sustained glucose-lowering effect[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: N-STZ rats[1]
Dosage: 1 or 10 mg/kg
Administration: P.o.;
Result: Improved insulin sensitivity and exerted sustained glucose-lowering effect.
Molecular Weight

614.77

Formula

C₃₆H₄₆N₄O₅

CAS No.
Shipping

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
SCO-267
Cat. No.:
HY-132265
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