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Results for "

(±)-8-Prenylnaringenin

" in MedChemExpress (MCE) Product Catalog:

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製品番号 製品名 Target 研究分野 構造式
  • HY-N2787
    8-​Prenylnaringenin
    1 Publications Verification

    		 PI3K Akt AMPK Sirtuin Reactive Oxygen Species (ROS) SOD Cardiovascular Disease Neurological Disease Metabolic Disease Endocrinology Cancer
    8-Prenylnaringenin is an orally active prenyl flavonoid. 8-Prenylnaringenin can be isolated from the hop spike Humulus lupulus. 8-Prenylnaringenin activates the PI3K/Akt pathway and the AMPK pathway, upregulates OXPHOS complexes (II, III, and V) and Sirt1, and reduces ROS production and SOD activity. 8-Prenylnaringenin improves muscle atrophy and obesity and inhibits angiogenesis. 8-Prenylnaringenin exhibits anticancer activity against glioblastoma and colon cancer. 8-Prenylnaringenin also has LH/FSH regulatory activity. 8-prenylnaringenin may be used in bone health research [8].
    8-​Prenylnaringenin
  • HY-126109
    (±)-8-Prenylnaringenin

    		Estrogen Receptor/ERR Apoptosis Metabolic Disease Endocrinology Cancer
    (±)-8-Prenylnaringenin, a natural prenylated flavonoid, is a potent phytoestrogen. (±)-8-Prenylnaringenin is an orally active selective estrogen receptor modulator (SERM) (Estrogen Receptor/ERR) that inhibits ERα and ERβ with IC50s of 57 nM and 68 nM, respectively. (±)-8-Prenylnaringenin has anticancer effects, and can be used for osteoporosis research .
    (±)-8-Prenylnaringenin
  • HY-P3350
    LS-BF1

    		Bacterial Infection
    LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].
    LS-BF1
  • HY-122416
    6,8-Diprenylnaringenin

    Lonchocarpol A; Senegalensin

    		 BCRP Metabolic Disease Cancer
    6,8-Diprenylnaringenin (Lonchocarpol A; Senegalensin), a hop prenylflavonoid, is a inhibitor of breast cancer resistance protein (BCRP/ABCG2). 6,8-Diprenylnaringenin inhibits ABCG2-mediated efflux of Mitoxantrone, and 3H-Methotrexate transport (IC50=0.41 μM) in HEK293 cells. 6,8-Diprenylnaringenin exhibits some estrogenicity, but its potency is less than 1% of that of 8-Prenylnaringenin .
    6,8-Diprenylnaringenin
  • HY-N9185
    6-Methyl-8-prenylnaringenin

    		Drug Derivative Others
    6-Methyl-8-prenylnaringenin is a natural flavonoid.
    6-Methyl-8-prenylnaringenin
  • HY-N16699
    4'-O-Methyl-8-prenylnaringenin

    		Bacterial Infection
    4'-O-Methyl-8-prenylnaringenin is a prenylated flavonoid compound with antibacterial activity, which can be isolated from propolis of the Solomon Islands. 4'-O-Methyl-8-prenylnaringenin exerts its antibacterial activity by enhancing cell penetration and damaging bacterial cell membranes or cell walls. The minimum inhibitory concentrations (MICs) against Staphylococcus aureus, Bacillus subtilis, and Pseudomonas aeruginosa are 32 μg/mL, 32 μg/mL, and 128 μg/mL, respectively .
    4'-O-Methyl-8-prenylnaringenin

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