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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Aerosol
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Aerosol" in MCE Product Catalog:
1
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Dornase alfa (rhDNase) is a recombinant human deoxyribonuclease I (rhDNase) that can specifically degrade extracellular DNA. Dornase alfa catalyzes the cleavage of DNA released by neutrophils in respiratory mucus, reduces sputum viscosity, thereby improving mucus clearance efficiency, reducing airway obstruction and alleviating inflammatory responses. Dornase alfa can be used to improve lung function (such as FEV_1) in cystic fibrosis (CF), reduce the risk of acute pulmonary exacerbations, and has good in vivo tolerability. Dornase alfa acts locally on the respiratory tract through aerosol inhalation, specifically improving the high viscosity of mucus caused by DNA accumulation and related respiratory symptoms .
Cat. No.: HY-112624J
CAS No.: 9004-54-0
Synonyms: Dextran 4; Dextran D4; Dextran T4(MW 3200-4800)
Cat. No.: HY-W034344
CAS No.: 2386-57-4
Cat. No.: HY-D0077
CAS No.: 195136-58-4
Synonyms: Oregon green 488
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2',7'-Difluorofluorescein (Oregon green 488) is a fluorescein derivative and a pH-sensitive fluorescent probe (pKa ~4.7). Upon excitation at 488 nm, 2',7'-Difluorofluorescein exhibits pH-sensitive fluorescence intensity through the formation of dianions, while its pH sensitivity decreases under excitation at 450 nm, allowing its use in ratiometric pH analysis. 2',7'-Difluorofluorescein can be used for the quantitative analysis of pH values in the range of 2-7 in submicron aerosol particles. 2',7'-Difluorofluorescein undergoes buffer-mediated and buffer-free excited-state proton transfer between different protonated forms, and its cationic form undergoes rapid excited-state deprotonation. 2',7'-Difluorofluorescein is resistant to photodegradation, maintains stable absorption and fluorescence properties within the physiological pH range, and serves as a fluorescent protein label, a component of Ca 2+ indicators, a fluorescent imaging agent, and an anisotropy probe .
Synonyms: Wy-48252
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Ritolukast (Wy-48252) is an orally active aerosol leukotriene (LTD4/E4) receptor antagonist. Ritolukast can be used to inhibit the bronchoconstriction caused by aerosol LTD4 in guinea pigs, with an ID50 of 0.5mg/kg .
Cat. No.: HY-105030
CAS No.: 74531-88-7
Synonyms: F 1865
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Tioxamast is an anti-allergic agent. Tioxamast can inhibit the synthesis and release of allergy mediators. Tioxamast blocks passive pulmonary anaphylactic shock induced by antigen aerosol in guinea-pig model .
Synonyms: R170591
JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg .
Cat. No.: HY-176512
CAS No.: 3100308-37-7
FO-32 is an ionizable lipid and mRNA delivery carrier with state-of-the-art aerosolized mRNA delivery capability. FO-32 delivers mRNA to mouse muscle, nasal mucosa, lung, as well as ferret lung epithelium (including conducting airways). FO-32 can be used in studies related to the generation of lipid nanoparticles (LNPs) and the optimization of drug delivery .
Cat. No.: HY-W093433
CAS No.: 10222-01-2
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2,2-Dibromo-2-cyanoacetamide is a non-oxidizing bactericide. 2,2-Dibromo-2-cyanoacetamide enhances bactericidal activity by reacting with sulfhydryl groups on the cell walls of microorganisms in aquatic environments to release bromide ions. 2,2-Dibromo-2-cyanoacetamide effectively inactivates Legionella pneumophila, rendering it non-culturable, and exhibits significantly higher killing efficacy against this bacterium in reservoir biofilms than in aerosol biofilms. 2,2-Dibromo-2-cyanoacetamide is suitable for legionellosis prevention and control as well as related research .
Cat. No.: HY-129785
CAS No.: 162141-96-0
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CP-220629 is a potent inhibitor of PDE4, with the IC50 of 0.44 μM. CP-220629 is efficacious in the guinea pig aerosolized antigen induced airway obstruction assay (ED50 2.0 mg/kg) .
Cat. No.: HY-185759
CAS No.: 2940240-84-4
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IR-19-Py is an ionizable lipid suitable for aerosolized mRNA delivery. When formulated into lipid nanoparticles, IR-19-Py delivers mRNA to nasal tissues in mice, achieving sustained nasal protein expression and dose-dependent pulmonary protein expression. IR-19-Py can be used in cystic fibrosis research .
Cat. No.: HY-115314
CAS No.: 101396-42-3
Synonyms: LG 30435
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Mequitamium iodide (LG 30435) is an antihistamine drug with antiallergic and bronchodilatory activity. Mequitamium iodide can effectively antagonize airway contraction and inflammatory responses induced by histamine and antigens. Mequitamium iodide has nanomolar affinity for the H1 and smooth muscle receptors of histamine and mequitin. Mequitamium iodide, when administered in aerosol form, significantly inhibits histamine- and antigen-induced increases in airway pressure in allergic mice. Mequitamium iodide reduces antigen-induced eosinophil accumulation in the airways. Mequitamium iodide also exhibits inhibitory effects on PAF-induced platelet aggregation and bronchoconstriction, and can be used in the study of allergic diseases such as rhinitis and asthma .
Cat. No.: HY-P12013
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
