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Baohuoside

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By Targets:	Apoptosis (2) Caspase (2) CDK (2) CXCR (2) Keap1-Nrf2 (2) NO Synthase (1) Reference Standards (2)
By Research Areas:	Cancer (4) Endocrinology (2) Infection (1) Inflammation/Immunology (5) Metabolic Disease (2)

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Natural
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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0011

Baohuoside I Maximum Cited Publications 18 Publications Verification Icariin-II; Icariside-II	CXCR Apoptosis	Inflammation/Immunology Endocrinology Cancer
Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity.

HY-N0260

Epmedin C 5+ Cited Publications Epimedin-C; Baohuoside-VI	Keap1-Nrf2 CDK Caspase	Infection Metabolic Disease Inflammation/Immunology Cancer
Epmedin C (Epimedin-C; Baohuoside-VI) is an orally active anti-inflammatory agent and immunomodulator that binds to multiple key proteins including UCP1, Caspase-1, CDK2 and Keap1. Epmedin C inhibits epithelial cell proliferation by disrupting the complex function of CDK2/Cyclin E. Epmedin C also upregulates Nrf2 expression, reduces ROS levels and inhibits pro-inflammatory cytokine secretion, thereby effectively restoring antibody production and alleviating tissue damage. Epmedin C has good safety with no hepatotoxicity or skin sensitization, and it has been used in studies on diseases such as obesity, Deoxynivalenol (HY-N6684)-induced immunotoxicity and mammary hyperplasia .

HY-N0875

IKarisoside A 3 Publications Verification Icarisoside-A; Baohuoside II	NO Synthase	Inflammation/Immunology
IKarisoside A (Icarisoside-A) is a natural flavonol glycoside and has anti-inflammatory properties.

HY-N2280

Baohuoside V	Others	Cancer
Baohuoside V is a flavonoid isolated from the dried herb of Epimedium davidii .

HY-N2290

Baohuoside VII	Others	Metabolic Disease
Baohuoside VII is a flavonoid isolated from Herba Epimedii, with anti-osteoporosis activities .

HY-N0011R

Baohuoside I (Standard) Icariin-II (Standard); Icariside-II (Standard)	Reference Standards CXCR Apoptosis	Inflammation/Immunology Endocrinology Cancer
Baohuoside I (Standard) is the analytical standard of Baohuoside I. This product is intended for research and analytical applications. Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity.

HY-N0260R

Epmedin C (Standard) Epimedin-C (Standard); Baohuoside-VI (Standard)	Reference Standards Keap1-Nrf2 CDK Caspase	Inflammation/Immunology
Epmedin C (Standard) is the analytical standard of Epmedin C. This product is intended for research and analytical applications. Epmedin C (Epimedin-C; Baohuoside-VI) is an orally active anti-inflammatory agent and immunomodulator that binds to multiple key proteins including UCP1, Caspase-1, CDK2 and Keap1. Epmedin C inhibits epithelial cell proliferation by disrupting the complex function of CDK2/Cyclin E. Epmedin C also upregulates Nrf2 expression, reduces ROS levels and inhibits pro-inflammatory cytokine secretion, thereby effectively restoring antibody production and alleviating tissue damage. Epmedin C has good safety with no hepatotoxicity or skin sensitization, and it has been used in studies on diseases such as obesity, Deoxynivalenol (HY-N6684)-induced immunotoxicity and mammary hyperplasia .

Baohuoside I Maximum Cited Publications 18 Publications Verification Icariin-II; Icariside-II	Flavonols Classification of Application Fields Anti-aging Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Epimedium koreanum Nakai Phenols Polyphenols Berberidaceae Inflammation/Immunology Disease Research Fields Endocrinology Source Classification Cancer	CXCR Apoptosis
Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity.

Epmedin C 5+ Cited Publications Epimedin-C; Baohuoside-VI	Flavonols Structural Classification Monophenols Flavonoids Classification of Application Fields Phenols Epimedium brevicornu Maxim. Plants Berberidaceae Inflammation/Immunology Disease Research Fields Source Classification	Keap1-Nrf2 CDK Caspase
Epmedin C (Epimedin-C; Baohuoside-VI) is an orally active anti-inflammatory agent and immunomodulator that binds to multiple key proteins including UCP1, Caspase-1, CDK2 and Keap1. Epmedin C inhibits epithelial cell proliferation by disrupting the complex function of CDK2/Cyclin E. Epmedin C also upregulates Nrf2 expression, reduces ROS levels and inhibits pro-inflammatory cytokine secretion, thereby effectively restoring antibody production and alleviating tissue damage. Epmedin C has good safety with no hepatotoxicity or skin sensitization, and it has been used in studies on diseases such as obesity, Deoxynivalenol (HY-N6684)-induced immunotoxicity and mammary hyperplasia .

IKarisoside A 3 Publications Verification Icarisoside-A; Baohuoside II	Flavonols Flavonoids Classification of Application Fields Epimedium brevicornu Maxim. Plants Berberidaceae Inflammation/Immunology Disease Research Fields Source Classification	NO Synthase
IKarisoside A (Icarisoside-A) is a natural flavonol glycoside and has anti-inflammatory properties.

Baohuoside V	Flavonols Flavonoids Classification of Application Fields Phenols Polyphenols Epimedium brevicornu Maxim. Plants Berberidaceae Disease Research Fields Cancer Source Classification	Others
Baohuoside V is a flavonoid isolated from the dried herb of Epimedium davidii .

Baohuoside VII	Flavonols Flavonoids Classification of Application Fields Phenols Polyphenols Metabolic Disease Epimedium brevicornu Maxim. Plants Berberidaceae Disease Research Fields Source Classification	Others
Baohuoside VII is a flavonoid isolated from Herba Epimedii, with anti-osteoporosis activities .

Baohuoside I (Standard) Icariin-II (Standard); Icariside-II (Standard)	Flavonols Structural Classification Human Gut Microbiota Metabolites Flavonoids Epimedium koreanum Nakai Phenols Polyphenols Plants Endogenous metabolite Berberidaceae Source Classification	Reference Standards CXCR Apoptosis
Baohuoside I (Standard) is the analytical standard of Baohuoside I. This product is intended for research and analytical applications. Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity.

Epmedin C (Standard) Epimedin-C (Standard); Baohuoside-VI (Standard)	Flavonols Structural Classification Monophenols Flavonoids Phenols Epimedium brevicornu Maxim. Plants Berberidaceae Source Classification	Reference Standards Keap1-Nrf2 CDK Caspase
Epmedin C (Standard) is the analytical standard of Epmedin C. This product is intended for research and analytical applications. Epmedin C (Epimedin-C; Baohuoside-VI) is an orally active anti-inflammatory agent and immunomodulator that binds to multiple key proteins including UCP1, Caspase-1, CDK2 and Keap1. Epmedin C inhibits epithelial cell proliferation by disrupting the complex function of CDK2/Cyclin E. Epmedin C also upregulates Nrf2 expression, reduces ROS levels and inhibits pro-inflammatory cytokine secretion, thereby effectively restoring antibody production and alleviating tissue damage. Epmedin C has good safety with no hepatotoxicity or skin sensitization, and it has been used in studies on diseases such as obesity, Deoxynivalenol (HY-N6684)-induced immunotoxicity and mammary hyperplasia .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Baohuoside

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Natural
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