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Results for "

C. parvum

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

1

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-B0956A
    Paromomycin

    Aminosidine

    		 Bacterial Parasite Endogenous Metabolite Infection
    Paromomycin (Aminosidine) is an orally active broad-spectrum aminoglycoside aminocyclitol. Paromomycin is produced by Streptomyces riomosus var. Paromomycinus. Paromomycin binding induces local conformational changes in the 16S rRNA A-site. Paromomycin exhibits inhibitory activity against C. parvum. Paromomycin can be used in research related to leishmaniasis, amoebiasis and cryptosporidiosis .
    Paromomycin
  • HY-103583
    KDU731

    		PI4K Parasite Infection
    KDU731, an orally active C. parvum PI4K inhibitor with an IC50 value of 25 nM, blocks Cryptosporidium infection in vitro and in vivo . KDU731 is a promising agent candidate for the treatment of diarrhea caused by Cryptosporidium and meets a broad range of safety .
    KDU731
  • HY-121495
    BKI-1369

    		Parasite Infection
    BKI-1369 is a bumped kinase inhibitor (BKI). BKI-1369 increases human Ether-a-go-go-related gene (hERG)-inhibitory activity with an IC50 of 1.52 μM. BKI-1369 reduces the parasite burden and diseases severity in the gnotobiotic pig model. BKI-1369 has been well characterized for potency, stability, metabolism, toxicity, pharmacokinetics and is potent against C. parvum in infected mice and calves .
    BKI-1369
  • HY-128214
    IMPDH-IN-3

    		IMPDH Parasite Infection
    IMPDH-IN-3 (Compound C67) is an inhibitor of C. parvum IMPDH (CpIMPDH) with an IC50 of 35 nM. IMPDH-IN-3 can be used in the research of anti-Cryptosporidium drugs .
    IMPDH-IN-3
  • HY-136307S
    Tizoxanide-d4 glucuronide

    		Isotope-Labeled Compounds Parasite Infection
    Tizoxanide-d4 glucuronide is the deuterium labeled Tizoxanide glucuronide. Tizoxanide glucuronide is the metabolite of Nitazoxanide (HY-B0217) and is cell-permeable to inhibit asexual and sexual stages development of parasite C. parvum .
    Tizoxanide-d4 glucuronide
  • HY-165555
    MMV665917

    		Parasite Infection
    MMV665917 is an orally active piperazine derivative with anti-Cryptosporidium parvum activity with an EC90 of 15 μM. MMV665917 significantly reduces the parasite load in a porcine model infected with C. hominis, decreases ovarian excretion, alleviates diarrhea symptoms and reduces intestinal mucosal damage. MMV665917 can be used for research on Cryptosporidium parvum disease .
    MMV665917
  • HY-118421
    Nullscript

    		Parasite HDAC Infection
    Nullscript is a negative control for Scriptaid. Nullscript is a known inactive analog of Scriptaid . Scriptaid is a representative HDAC inhibitor . Nullscript inhibits Cryptosporidium (C. parvum) growth with the IC50 value of 2.1 μM .
    Nullscript
  • HY-128398
    CpCDPK1/TgCDPK1-IN-2

    		Parasite Infection
    CpCDPK1/TgCDPK1-IN-2 (Compound 7r) is a CpCDPK1 and TgCDPK1 inhibitor with IC50 values of 12 and 5 nM, respectively. CpCDPK1/TgCDPK1-IN-2 can be used in the research of apicomplexan protozoa-related diseases, such as the research of T. gondii, C. parvum and C. hominus infection .
    CpCDPK1/TgCDPK1-IN-2
  • HY-128399
    CpCDPK1/TgCDPK1-IN-3

    		Parasite Infection
    CpCDPK1/TgCDPK1-IN-3 (Compound 20) is a CpCDPK1 and TgCDPK1 inhibitor with IC50 values of 0.003 and 0.0036 µM, respectively. CpCDPK1/TgCDPK1-IN-3 can be used in the research of apicomplexan protozoa-related diseases, such as the research of T. gondii, C. parvum and C. hominus infection .
    CpCDPK1/TgCDPK1-IN-3
  • HY-172098
    CpNMT-IN-1

    		Parasite Infection
    CpNMT-IN-1 (Compound 11e) is an against N-myristoyltransferase of C. parvum (CpNMT) inhibitor with an IC50 value of 2.5 μM. CpNMT-IN-1 also inhibits the growth of C. parvum with an EC50 value of 6.9 μM .
    CpNMT-IN-1
  • HY-158776
    SLU-10482

    		Parasite Infection
    SLU-10482 is an orally active anti-parasitic agent, that inhibits Cryptosporidium parvum with an IC50 of 0.0687 μM. SLU-10482 exhibits anti-infective efficacy in C. parvum infected mice with an AC50 of 0.0686 μM .
    SLU-10482
  • HY-103583R
    KDU731 (Standard)

    		Reference Standards PI4K Parasite Infection
    KDU731 (Standard) is the analytical standard of KDU731 (HY-103583). This product is intended for research and analytical applications. KDU731, an orally active C. parvum PI4K inhibitor with an IC50 value of 25 nM, blocks Cryptosporidium infection in vitro and in vivo . KDU731 is a promising agent candidate for the treatment of diarrhea caused by Cryptosporidium and meets a broad range of safety .
    KDU731 (Standard)

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