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Cat. No.: HY-128214

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IMPDH-IN-3

Name: IMPDH-IN-3
Brand: MedChemExpress
SKU: HY-128214
Price: 50.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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IMPDH-IN-3 (Compound C67) is an inhibitor of C. parvum IMPDH (CpIMPDH) with an IC₅₀ of 35 nM. IMPDH-IN-3 can be used in the research of anti-Cryptosporidium drugs.

For research use only. We do not sell to patients.

Purity : 90%
CAS No.: 401822-29-5
Formula: C₁₈H₁₃ClN₄OS
Molecular Weight:368.84

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

IMPDH-IN-3 Chemical Structure

CAS No.: 401822-29-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

IMPDH-IN-3 (Compound C67) is an inhibitor of C. parvum IMPDH (CpIMPDH) with an IC₅₀ of 35 nM. IMPDH-IN-3 can be used in the research of anti-Cryptosporidium drugs^[1].

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Chemical Information

CAS No. 401822-29-5
Appearance Solid
Molecular Weight 368.84
Formula C₁₈H₁₃ClN₄OS
Color White to off-white
SMILES

O=C(NC1=CC=C(Cl)C=C1)CN2C3=CC=CC=C3N=C2C4=CN=CS4
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (283 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kirubakaran S, et al. Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1985-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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