1. Anti-infection
  2. Parasite
  3. BKI-1369

BKI-1369 

Cat. No.: HY-121495
Handling Instructions

BKI-1369 is a bumped kinase inhibitor (BKI). BKI-1369 increases human Ether-a-go-go-related gene (hERG)-inhibitory activity with an IC50 of 1.52 μM. BKI-1369 reduces the parasite burden and diseases severity in the gnotobiotic pig model. BKI-1369 has been well characterized for potency, stability, metabolism, toxicity, pharmacokinetics and is potent against C. parvum in infected mice and calves.

For research use only. We do not sell to patients.

BKI-1369 Chemical Structure

BKI-1369 Chemical Structure

CAS No. : 1951431-22-3

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Description

BKI-1369 is a bumped kinase inhibitor (BKI). BKI-1369 increases human Ether-a-go-go-related gene (hERG)-inhibitory activity with an IC50 of 1.52 μM. BKI-1369 reduces the parasite burden and diseases severity in the gnotobiotic pig model. BKI-1369 has been well characterized for potency, stability, metabolism, toxicity, pharmacokinetics and is potent against C. parvum in infected mice and calves[1].

IC50 & Target

IC50: 1.52 μM (hERG)[1]

Molecular Weight

417.51

Formula

C₂₃H₂₇N₇O

CAS No.

1951431-22-3

SMILES

NC1=C2C(N(CC3CCN(C)CC3)N=C2C4=CC=C5N=C(OCC)C=CC5=C4)=NC=N1

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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BKI-1369
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