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Results for "

CLP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Androgen Receptor (1) Bacterial (2) CD28 (2) HCN Channel (1) Potassium Channel (2) Sirtuin (1) Small Interfering RNA (siRNA) (2) β-catenin (1)
By Research Areas:	Cancer (1) Infection (2) Inflammation/Immunology (6) Metabolic Disease (1) Neurological Disease (3)

Inhibitors & Agonists

Peptides

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-141487

CLP-3094 2 Publications Verification	Androgen Receptor	Metabolic Disease Inflammation/Immunology
CLP-3094 is a potent BF3 (binding function 3)-directed inhibitor of the androgen receptor (AR). CLP-3094 inhibits AR transcriptional activity (IC₅₀=4 μM) . CLP-3094 is a selective, potent GPR142 antagonist .

HY-110143

CLP257	Potassium Channel	Neurological Disease
CLP257 is a selective K ⁺-Cl ⁻ cotransporter KCC2 activator with an EC₅₀ of 616 nM. CLP257 is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4. CLP257 restores impaired Cl ⁻ transport in neurons with diminished KCC2 activity. CLP257 alleviates hypersensitivity in rats with neuropathic pain. CLP257 modulates plasmalemmal KCC2 protein turnover post-translationally .

HY-103023

CLP290 1 Publications Verification	Potassium Channel	Neurological Disease
CLP290 is an orally available activator of the neuron-specific K ⁺-Cl ⁻ cotransporter KCC2, displays potential for treatment of a wide range of neurological and psychiatric indications. CLP290 can significantly lower blood arginine-vasopressin (AVP) and glucose levels in STZ rats .

HY-RS02829

CLP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CLP1 Human Pre-designed siRNA Set A contains three designed siRNAs for CLP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CLP1 Human Pre-designed siRNA Set A CLP1 Human Pre-designed siRNA Set A

HY-RS02832

CLPS Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CLPS Human Pre-designed siRNA Set A contains three designed siRNAs for CLPS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CLPS Human Pre-designed siRNA Set A CLPS Human Pre-designed siRNA Set A

HY-12716A

BRL-44408 maleate	Adrenergic Receptor	Neurological Disease
BRL-44408 maleate is an α2A-adrenoceptor antagonist (K_i: 8.5 nM). BRL-44408 maleate has antidepressant and analgesic activity. BRL-44408 also improves cecal ligation puncture (CLP)-induced acute lung injury .

HY-119102

BPU-11	HCN Channel	Inflammation/Immunology
BPU-11 is a hyperpolarization-activated cyclic nucleotide-gated (HCN) C-linker pocket (CLP) HCN4 CLP ligand. BPU-11 can be used for the research of congenital immune disease .

HY-163409

CGK012	β-catenin	Inflammation/Immunology Cancer
CKG012 is an inhibitor for Wnt/βcatenin signaling pathway. CGK012 inhibits release of HMGB1 and transcription of β-catenin, exhibits attenuating activities against cecal ligation and puncture (CLP)-induced sepsis and multiple myeloma cancer .

HY-N1388

Tussilagone 1 Publications Verification
Tussilagone, a major active component in Tussilago farfara, has anti-inflammatory effect. Tussilagone ameliorates inflammatory responses in dextran sulphate sodium-induced murine colitis. Tussilagone inhibits the inflammatory response and improves survival in cecal ligation and puncture (CLP)-induced septic mice .

HY-149426

SIRT5 inhibitor 7	Sirtuin	Inflammation/Immunology
SIRT5 inhibitor 7 (compound 58) is a substrate-competitive and selective SIRT5 inhibitor with anti-inflammatory activity. SIRT5 inhibitor 7 has renal protective effects and regulates protein succinylation and the release of pro-inflammatory cytokines. SIRT5 inhibitor 7 has in vivo activity in AKI mouse models of lipopolysaccharide (LPS) and cecal ligation/perforation (CLP)-induced sepsis-related acute kidney injury .

HY-P1698

Reltecimod AB-103	Bacterial CD28	Infection Inflammation/Immunology
Reltecimod (AB-103) is a T-cell-specific surface glycoprotein CD28 (TP44) antagonist. Reltecimod has beneficial effects against different bacterial infections, their exotoxins and endotoxins, and ionizing radiation. Reltecimod modulates the inflammatory response by targeting and attenuating the critical CD28/B7-2 co-stimulatory pathway, without inhibiting it. Reltecimod can be used to research necrotizing soft-tissue infections (NSTIs) .

HY-P1698B

Reltecimod TFA AB-103 TFA	Bacterial CD28	Infection Inflammation/Immunology
Reltecimod (AB-103) TFA is a T-cell-specific surface glycoprotein CD28 (TP44) antagonist. Reltecimod TFA has beneficial effects against different bacterial infections, their exotoxins and endotoxins, and ionizing radiation. Reltecimod TFA modulates the inflammatory response by targeting and attenuating the critical CD28/B7-2 co-stimulatory pathway, without inhibiting it. Reltecimod TFA can be used to research necrotizing soft-tissue infections (NSTIs) .

Cat. No.	Product Name	Target	Research Area

HY-P1698B

Reltecimod TFA AB-103 TFA	Bacterial CD28	Infection Inflammation/Immunology
Reltecimod (AB-103) TFA is a T-cell-specific surface glycoprotein CD28 (TP44) antagonist. Reltecimod TFA has beneficial effects against different bacterial infections, their exotoxins and endotoxins, and ionizing radiation. Reltecimod TFA modulates the inflammatory response by targeting and attenuating the critical CD28/B7-2 co-stimulatory pathway, without inhibiting it. Reltecimod TFA can be used to research necrotizing soft-tissue infections (NSTIs) .

HY-P1698

Reltecimod AB-103	Bacterial CD28	Infection Inflammation/Immunology
Reltecimod (AB-103) is a T-cell-specific surface glycoprotein CD28 (TP44) antagonist. Reltecimod has beneficial effects against different bacterial infections, their exotoxins and endotoxins, and ionizing radiation. Reltecimod modulates the inflammatory response by targeting and attenuating the critical CD28/B7-2 co-stimulatory pathway, without inhibiting it. Reltecimod can be used to research necrotizing soft-tissue infections (NSTIs) .

Species:	Human (3)
Tag:	His (3) Tag Free (1) GST (1)
Source:	E. coli (5)

Cat. No.	Compare	Product Name	Species	Source

HY-P72110

	CALML3 Protein, Human (GST) CALL3_HUMAN; CALML3; Calmodulin like 3; Calmodulin related protein NB 1; Calmodulin-like protein 3; Calmodulin-related protein NB-1; CaM like protein; CaM-like protein; CLP; OTTHUMP00000019004	Human	E. coli
	The CALML3 protein has a dual role, acting as a specific light chain of unconventional myosin 10 (MYO10) and enhancing MYO10 translation. CALML3 has a potential molecular chaperone role and contributes to the synthesis of the emerging MYO10 heavy chain protein. CALML3 Protein, Human (GST) is the recombinant human-derived CALML3 protein, expressed by E. coli , with N-GST labeled tag. The total length of CALML3 Protein, Human (GST) is 149 a.a., with molecular weight of ~43.9 kDa.

HY-P701867

	ClpC1 NTD Protein, Mycobacterium tuberculosis CLPC1; ATP-dependent CLP protease ATP-binding subunit CLPC1	Others	E. coli
	ClpC1 NTD Protein, the ATP-dependent specificity component of the Clp protease, directs the protease to specific substrates and exhibits chaperone functions independently of ClpP. It plays a crucial role in the targeted degradation of substrates, such as the anti-sigma-E factor RseA, in the presence of ClpP2. ClpC1 NTD Protein, Mycobacterium tuberculosis is the recombinant ClpC1 NTD protein, expressed by E. coli , with tag free. The total length of ClpC1 NTD Protein, Mycobacterium tuberculosis is 145 a.a., .

HY-P701868

	ClpC1 NTD Protein, Mycobacterium tuberculosis (His) CLPC1; ATP-dependent CLP protease ATP-binding subunit CLPC1	Others	E. coli
	ClpC1 NTD Protein, the ATP-dependent specificity component of the Clp protease, directs the protease to specific substrates and exhibits chaperone functions independently of ClpP. It plays a crucial role in the targeted degradation of substrates, such as the anti-sigma-E factor RseA, in the presence of ClpP2. ClpC1 NTD Protein, Mycobacterium tuberculosis (His) is the recombinant ClpC1 NTD protein, expressed by E. coli , with N-6*His labeled tag. The total length of ClpC1 NTD Protein, Mycobacterium tuberculosis (His) is 145 a.a., .

HY-P74586

	S100A10 Protein, Human (His) Protein S100-A10; p11; S100A10; ANX2LG; CAL1L; CLP11	Human	E. coli
	S100A10 Protein is pivotal in modulating protein phosphorylation by promoting ANXA2/p36 dimerization. The ANXA2 monomer is the favored substrate for tyrosine-specific kinase activity in vitro. A heterotetramer, composed of S100A10/p11 and ANXA2/p36, highlights intricate regulatory dynamics. This interaction landscape includes SCN10A and TASOR, showcasing S100A10's multifaceted involvement in cellular processes. S100A10 Protein, Human (His) is the recombinant human-derived S100A10 protein, expressed by E. coli, with N-6*His labeled tag. The total length of S100A10 Protein, Human (His) is 96 a.a., with molecular weight of ~13 kDa.

HY-P71647

	CHID1 Protein, Human (His) CHID1; CHID1_HUMAN; Chitinase domain containing 1; Chitinase domain-containing protein 1; SI-CLP; SICLP; Stabilin 1 interacting chitinase like protein; Stabilin-1-interacting chitinase-like protein	Human	E. coli
	CHID1 Protein, a saccharide- and LPS-binder, implies roles in pathogen sensing and endotoxin neutralization. Its ligand specificity, linked to oligosaccharide length, shows a preference for chitotetraose. CHID1's interaction with STAB1 suggests potential involvement in cellular processes related to STAB1 interactions. CHID1 Protein, Human (His) is the recombinant human-derived CHID1 protein, expressed by E. coli , with N-His labeled tag. The total length of CHID1 Protein, Human (His) is 374 a.a., with molecular weight of ~46.8 kDa.


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Cat. No.	Product Name	Application	Reactivity

HY-P81930

CLPP Antibody (YA1675)

Endopeptidase CLP
WB, IHC-P, IP Human, Mouse, Rat
HY-P81820

PDLIM1 Antibody (YA1565)

PDLIM1; CLIM1; CLP36; PDZ and LIM domain protein 1; C-terminal LIM domain protein 1; Elfin; LIM domain protein CLP-36
WB, ICC/IF, IP Human, Mouse, Rat
HY-P83069

CLPX Antibody (YA2814)

ATP-dependent CLP protease ATP-binding subunit CLPX-like; mitochondrial; CLPX
WB, ICC/IF Human, Mouse, Rat, Hamster

HY-P80889

S100A10 Antibody (YA675) S100A10; 42C; ANX2L; ANX2LG; CAL1L; CLP11; Ca[1]; GP11; P11; p10	WB, ICC/IF, IP	Human, Mouse, Rat
S100A10 Antibody (YA675) is a non-conjugated and Mouse origined monoclonal antibody about 11 kDa, targeting to S100A10 (6F4). It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

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